How different post-workout meals affect muscle protein building
Official title: Impact of Food Combinations on the Stimulation of Post-exercise Muscle Protein Synthesis in Healthy Adults
Run by University of Illinois at Urbana-Champaign · NCT07367854 · Data updated 2026-11-12
This trial tests whether eating potato plus beef, bread plus beef, or beef alone right after resistance exercise changes muscle protein building in healthy, recreationally active young adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years to 40 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | University of Illinois at Urbana-Champaign Academic / other |
| Locations | 2 sites (Urbana, Illinois and 1 other locations) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | October 31, 2027 |
| Study ends | November 1, 2028 |
| Registry record updated | May 1, 2026 |
| Trial ID | NCT07367854 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy, recreationally active adults about 19–40 years old who are weight-stable and, if female, premenopausal with regular menstrual cycles.
✕Probably not a fit
Older adults, sedentary individuals, pregnant people, those with irregular menstrual cycles, or anyone with medical conditions that affect protein metabolism are unlikely to get direct benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Fifteen recreationally active young adults will take part in a semi-crossover randomized protocol where each participant completes a resistance exercise session followed by one of three meal conditions on separate visits. Participants receive stable isotope tracer infusions and undergo repeated blood draws and muscle biopsies to track whole-body leucine kinetics, amino acid levels, anabolic signaling, and myofibrillar protein synthesis rates. The three post-exercise conditions are a russet potato with lean ground beef, white bread with lean ground beef, or lean beef alone, with meal macronutrients closely matched. Data will compare how the food matrix and carbohydrate/fiber differences influence post-exercise protein metabolism.
Why it matters
Potential benefit: If successful, the results could help people choose post-exercise meals that better support muscle repair and growth.
How similar studies have gone: Prior research shows that consuming protein, especially leucine-rich sources, after resistance exercise increases muscle protein synthesis, but direct comparisons of whole-food combinations like potato versus bread with beef are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 19-40 yrs * Pre-menopausal * Recreationally-active * Weight stable for prior 6 months Exclusion Criteria: * Age outside of range (20 - 35 yrs) * Pregnancy * Irregular menstrual cycles (i.e., \~21 day or \~35 day cycle) * Participation in previous research using L-\[1-13C\] leucine and L-\[ring-2H5\] phenylalanine * Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.)
Where it's running
-
Louise Freer Hall
Urbana, Illinois, United States Recruiting -
Louise Freer Hall
Urbana, Illinois, United States Not yet recruiting
Study contacts
- Study coordinator: Nicholas A Burd (Full Professor), PhD
- Email: naburd@illinois.edu
- Phone: 2172440970
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.