Clinical trial Recruiting at 1 site Interventional Ages 19 to 40

How different post-workout meals affect muscle protein building

Official title: Impact of Food Combinations on the Stimulation of Post-exercise Muscle Protein Synthesis in Healthy Adults

Run by University of Illinois at Urbana-Champaign · NCT07367854 · Data updated 2026-11-12

This trial tests whether eating potato plus beef, bread plus beef, or beef alone right after resistance exercise changes muscle protein building in healthy, recreationally active young adults.

Quick facts

Study typeInterventional
Ages19 Years to 40 Years
SexAll
Enrollment15 (estimated)
SponsorUniversity of Illinois at Urbana-Champaign
Academic / other
Locations2 sites (Urbana, Illinois and 1 other locations)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedOctober 31, 2027
Study endsNovember 1, 2028
Registry record updatedMay 1, 2026
Trial IDNCT07367854 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy, recreationally active adults about 19–40 years old who are weight-stable and, if female, premenopausal with regular menstrual cycles.

Probably not a fit

Older adults, sedentary individuals, pregnant people, those with irregular menstrual cycles, or anyone with medical conditions that affect protein metabolism are unlikely to get direct benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Fifteen recreationally active young adults will take part in a semi-crossover randomized protocol where each participant completes a resistance exercise session followed by one of three meal conditions on separate visits. Participants receive stable isotope tracer infusions and undergo repeated blood draws and muscle biopsies to track whole-body leucine kinetics, amino acid levels, anabolic signaling, and myofibrillar protein synthesis rates. The three post-exercise conditions are a russet potato with lean ground beef, white bread with lean ground beef, or lean beef alone, with meal macronutrients closely matched. Data will compare how the food matrix and carbohydrate/fiber differences influence post-exercise protein metabolism.

Why it matters

Potential benefit: If successful, the results could help people choose post-exercise meals that better support muscle repair and growth.

How similar studies have gone: Prior research shows that consuming protein, especially leucine-rich sources, after resistance exercise increases muscle protein synthesis, but direct comparisons of whole-food combinations like potato versus bread with beef are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 19-40 yrs
* Pre-menopausal
* Recreationally-active
* Weight stable for prior 6 months

Exclusion Criteria:

* Age outside of range (20 - 35 yrs)
* Pregnancy
* Irregular menstrual cycles (i.e., \~21 day or \~35 day cycle)
* Participation in previous research using L-\[1-13C\] leucine and L-\[ring-2H5\] phenylalanine
* Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.)

Where it's running

  • Louise Freer Hall
    Urbana, Illinois, United States
    Recruiting
  • Louise Freer Hall
    Urbana, Illinois, United States
    Not yet recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.