Stable isotope tracing in adults with obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a small crossover metabolic study in eight adults with obesity using stable isotope–labeled oral drinks to trace glucose and amino acid handling. In one arm participants consume six hourly caloric drinks containing two stable isotopes with repeated blood, breath, urine sampling and muscle biopsies. In the other arm participants drink a single 75 g glucose drink labeled with two glucose isotopes and provide serial blood and breath samples over three hours. Initial consent and screening questionnaires are completed virtually and eligible participants (ages 19–59, BMI ≥30 kg/m2, low habitual activity) attend on-site visits at the University of Illinois for fasting tests and biopsies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ages 19-59
* Obese \>/= 30 kg/m\^2 and \>/= 102 cm for males and \>/= 88 cm for females
* Godin Leisure-time or exercise questionnaire \<14 units

Exclusion Criteria:

1. Pregnant or become pregnant
2. Any known food allergies
3. Smoker
4. Are physically active
5. Have any known metabolic diseases
6. Have been weight unstable within the last 6 months (lost or gained \>10% of body mass)
7. Non eumenorrheic or on a hormonal birth control

Where it's running

• Freer Hall - University of Illinois
  Urbana, Illinois, United States Recruiting

Study contacts

• Study coordinator: Nicholas Burd (Associate Professor), PhD
• Email: naburd@illinois.edu
• Phone: 2172440970

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.