How blood loss varies in orthopedic prosthetic surgery with different techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective observational study evaluating blood loss in prosthetic orthopedic surgeries over a year. It analyzes preoperative hemoglobin and hematocrit, then tracks values on days 1–3 and day 7 after surgery. The study also looks at how intraoperative techniques and perioperative practices relate to bleeding, recovery, and complications. Primary goal is to understand the extent and variability of blood loss compared with published literature. Secondary outcomes include postoperative course, transfusion needs, and any complications related to bleeding or recovery.

Why it matters

Who can join: the full rules

Inclusion criteria:

\- Adult patients in ASA Class I-II-III undergoing prosthetic surgery, as a first-time implant

Exclusion criteria:

* Patients who did not receive tranexamic acid prophylaxis (pre-operative and post- operative doses) and are therefore not comparable with the vast majority of cases.
* Reintervention, as bleeding depends on a variable that is not constant, namely the initial implant

Where it's running

• I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
  Milan, Milan, Italy Recruiting

Study contacts

• Principal investigator: Giorgio Oriani, P.I. — IRCCS Laleazzi Sant Ambrogio Site San Siro Institute
• Study coordinator: Giorgio Oriani, Principal Investigator
• Email: gorian@alice.it
• Phone: +39335225452

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.