Hormonal profiles and isotretinoin response in adult women with acne

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study explores whether initial blood levels of DHEAS, FSH, and LH are associated with clinical response to systemic isotretinoin in women aged 18 and older with moderate to severe acne vulgaris. Participants are adult women planning isotretinoin therapy and not currently on hormonal treatments. The research examines baseline hormone measurements to identify potential predictors of treatment outcome in a real-world setting. It is conducted at Biruni University Hospital in Istanbul and does not specify an intervention beyond routine isotretinoin treatment. Results could inform future patient stratification and personalized management approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients aged ≥18 years.
* Clinical diagnosis of moderate to severe acne vulgaris.
* Planned initiation of systemic isotretinoin therapy.
* Ability to provide informed consent

Exclusion Criteria:

* Use of hormonal therapy (oral contraceptives, antiandrogens, systemic corticosteroids) within the last 3 months.
* Contraindications to isotretinoin therapy.

Where it's running

• Biruni University Hospital
  Küçükçekmece, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ömer Mert, Specialist Dermatologist MD
• Email: omermert95@gmail.com
• Phone: +905396778884

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.