Higher zinc supplementation to boost weight gain in extremely premature infants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Premature infants are at risk for zinc deficiency due to limited in utero accumulation and small zinc stores after birth. This open-label randomized trial compares two zinc dosing regimens, 1 mg/kg/day versus 3 mg/kg/day, from birth to 36 weeks PMA or discharge, to see which improves weight velocity. Secondary outcomes include head circumference and length velocity, bronchopulmonary dysplasia severity, and length of hospital stay. Safety monitoring will note possible GI intolerance and anemia. Conducted at Wellstar Children's Hospital of Georgia with Augusta University as sponsor, the study follows standard NICU feeding practices with dose adjustments per usual care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Birth weight: 750-1500 grams

Exclusion Criteria:

* Spontaneous Intestinal Perforation (SIP)
* Necrotizing enterocolitis (NEC)
* Gastrointestinal anomalies (gastroschisis, omphalocele, or intestinal atresia)
* Infants on formula milk

Where it's running

• Wellstar Childrens Hospital of Georgia
  Augusta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Lauren Walker, DO — Augusta University
• Study coordinator: Julia Newman, DO
• Email: junewman@augusta.edu
• Phone: 706-721-2331

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.