Remote-controlled oxygen therapy for preterm infants with BPD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This national, prospective, multicenter pilot in the Czech Republic will enroll about 70 preterm infants with bronchopulmonary dysplasia who are discharged on low-flow nasal cannulas. Continuous home pulse oximetry data will be transmitted to clinicians who will adjust oxygen using pre-established protocols aimed at earlier and safer weaning. The project aims to validate the organization and feasibility of remotely managed home oxygen therapy and to prepare a proposal for a national care methodology. It is supported by national and European funds and has received ethical approvals from local committees.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* infants born before 31+6 weeks gestation
* signed consent for participation in the project and consent for the processing of personal data
* diagnosed with bronchopulmonary dysplasia
* type of pulmonary ventilation - low-flow nasal cannulas

Exclusion Criteria:

* unsigned consent for participation in the project and/or consent for the processing of personal data
* child diagnosed with conditions other than bronchopulmonary dysplasia (BPD) at high risk of long-term hypoxia - selected chronic cardiovascular, neurological, and muscular diseases, e.g., significant congenital heart defects, congenital central nervous system developmental disorders, genetic diseases associated with the risk of hypoventilation, central apneas, severe early obstructive sleep apnea
* other chronic respiratory diseases besides BPD - e.g., cystic fibrosis, chronic aspiration
* insufficient therapy through long-term home oxygen therapy
* tracheostomy

Where it's running

• České Budějovice Hospital
  České Budějovice, Czech Republic, Czechia Recruiting
• University Hospital Olomouc
  Olomouc, Czech Republic, Czechia Recruiting
• General University Hospital
  Prague, Czech Republic, Czechia Recruiting
• Institute for the Care of Mother and Child
  Prague, Czech Republic, Czechia Recruiting

Study contacts

• Study coordinator: Daniela Dokoupilová, MSc
• Email: daniela.dokoupilova@uzis.cz
• Phone: +420725441408

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.