High-Intensity Interval Exercise in BronchiectasisPatients
Official title: Investigation of the Effectiveness of High-Intensity Interval Exercise in Bronchiectasis Patients
Run by Saglik Bilimleri Universitesi · NCT07805174 · Data updated 2026-11-12
This study tests whether adding high‑intensity interval exercise to airway clearance helps people with bronchiectasis feel better and function more, compared with airway clearance alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 42 (estimated) |
| Sponsor | Saglik Bilimleri Universitesi Academic / other |
| Locations | 1 site (Ankara, Keçiören) |
| Status | Recruiting |
| Started | March 27, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | May 29, 2027 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT07805174 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with clinically and radiologically confirmed non‑CF bronchiectasis, stable for at least four weeks, without cognitive impairment.
✕Probably not a fit
Patients with unstable cardiovascular conditions, recent respiratory infections, or other high‑risk factors may not benefit or participate safely.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial investigates the effects of high‑intensity interval exercise (HIIE) combined with airway clearance techniques on respiratory function, functional capacity, muscle strength, and quality of life in adults with non‑CF bronchiectasis. Participants are assigned to either HIIE plus airway clearance or airway clearance alone, with sessions three days per week. The trial aims to see if HIIE can reduce dyspnea, cough, and fatigue while improving overall outcomes. Safety exclusions are in place for cardiovascular and other high‑risk conditions. The study is led by Saglik Bilimleri University with recruitment at Gulhane Faculty of Physiotherapy and Rehabilitation in Ankara, Turkey.
Why it matters
Potential benefit: If successful, patients could experience better breathing, greater physical capacity, and improved daily life.
How similar studies have gone: Previous trials in similar respiratory populations suggest feasibility and potential benefits of combined exercise and airway clearance, but evidence in bronchiectasis is limited and further confirmation is needed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Being over 18 years of age 2. Having a clinical and radiological diagnosis of non-cystic fibrosis bronchiectasis 3. Absence of cognitive impairment (MMT\>24) 4. Being clinically stable (not having experienced any exacerbation in the last 4 weeks) Exclusion Criteria: 1. Presence of any disease that may affect compliance with exercise (Unstable angina (within the last month), recent myocardial infarction (heart attack), uncontrolled arrhythmias, severe aortic stenosis, decompensated heart failure, severe pulmonary hypertension, acute respiratory tract infection, severe hypoxemia at rest (\<85%), orthopedic or neurological problems that impede walking, severe anemia, acute infections, very high resting blood pressure (systolic \>180-200 mmHg, diastolic \>100-110 mmHg), psychological issues, etc.) 2. Smoking 3. Chronic alcoholism that may affect exercise safety (More than 1 drink per day on average for women, more than 2 drinks per day on average for men (1 standard drink ≈ 10-14 g of alcohol) 4. Presence of any respiratory tract disease other than bronchiectasis 5. After incremental shuttle walk test arterial oxygen saturation \<80% 6. Participation in a structured exercise program within the last 6 months
Where it's running
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Gulhane Faculty of Physiotherapy and Rehabilitation
Ankara, Keçiören, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mustafa Ertuğrul YAŞA, Associate Professor
- Email: mustafaertugrul.yasa@sbu.edu.tr
- Phone: 0312 304 61 97
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.