Clinical trial Recruiting at 1 site Observational

High-dose statin therapy for patients with acute coronary syndrome

Official title: The Protective Effect of Early High Dose High-intensity Statins on Cardiovascular and Renal Events in Patients With Acute Coronary Syndrome

Run by Centro Cardiopatici Toscani · NCT04087200 · Data updated 2026-11-12

This study is testing if giving high doses of statins right away to patients with acute coronary syndrome can improve their heart health during and after their hospital stay.

More Acute Coronary Syndrome trials

Quick facts

Study typeObservational
SexAll
Enrollment2500 (estimated)
SponsorCentro Cardiopatici Toscani
Academic / other
Locations1 site (Prato)
StatusRecruiting
StartedDecember 1, 2016
Main results expectedDecember 1, 2025
Study endsDecember 1, 2026
Registry record updatedSeptember 12, 2019
Trial IDNCT04087200 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients experiencing acute coronary syndrome who are scheduled for early invasive strategies.

Probably not a fit

Patients with contraindications to statin therapy or those who refuse consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of early high-dose statin therapy on patients admitted for acute coronary syndrome (ACS), including both STEMI and NSTEMI. Patients who are statin-naive or already on statins will receive either atorvastatin or rosuvastatin immediately upon admission, prior to any invasive procedures. The study will track various cardiac and renal parameters during hospitalization and conduct follow-ups one month and one year after discharge to assess outcomes.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risk of cardiovascular and renal events in patients with acute coronary syndrome.

How similar studies have gone: Other studies have shown promising results with high-dose statin therapy in similar patient populations, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Acute coronary syndrome (ST elevation and non ST elevation)
* Early invasive strategy

Exclusion Criteria:

* contraindication to statin therapy
* refusal of consent

Where it's running

  • Cardiology Division, Prato Hospital
    Prato, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.