Clinical trial Recruiting at 1 site Observational Ages 18 to 40

Changes in Depression and How Patients Perceive Their Appearance After Double-Jaw Orthognathic Surgery

Official title: Evaluation of Changes in Depressive Symptom Levels and Subjective Esthetic Perception in Patients With Different Types of Malocclusion Following Orthognathic Surgery

Run by Kırıkkale University · NCT07702448 · Data updated 2026-11-12

This study tests whether undergoing bimaxillary orthognathic surgery changes depressive symptoms and self-perceived facial appearance in adults with dentofacial deformities.

Quick facts

Study typeObservational
Ages18 Years to 40 Years
SexAll
Enrollment18 (estimated)
SponsorKırıkkale University
Academic / other
Locations1 site (Kirikkale, Kırıkkale)
StatusRecruiting
StartedJune 20, 2026
Main results expectedJune 20, 2027
Study endsJuly 20, 2027
Registry record updatedJuly 16, 2026
Trial IDNCT07702448 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–40 with an indication for bimaxillary orthognathic surgery, no systemic or psychiatric disorders, and who complete questionnaires 1 week before and 6 months after surgery.

Probably not a fit

Patients not undergoing bimaxillary surgery, with psychiatric conditions, systemic diseases, or who do not complete follow-up questionnaires may see no demonstrated benefit in these outcomes.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study will compare depressive symptoms and subjective esthetic perception in adults aged 18 to 40 with malocclusions who undergo bimaxillary orthognathic surgery. Patients will complete validated questionnaires before surgery and at a 6-month follow-up, using anonymized clinical data and self-reported measures. Data elements include demographics, social media use, and subjective esthetic and mood assessments. The goal is to understand how surgical correction may impact psychological well-being and perceived attractiveness to inform patient evaluation and planning. The study is conducted at the Faculty of Dentistry, Kirikkale University, led by Kirikkale University with no listed collaborators.

Why it matters

Potential benefit: If successful, the study could clarify how this surgery affects mood and self-image, helping clinicians counsel patients and tailor care.

How similar studies have gone: Other research has linked orthognathic procedures to changes in quality of life and psychological outcomes, though this exact assessment in a prospective, observational design is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 40 years.
* Individuals without systemic diseases.
* Patients with an indication for bimaxillary orthognathic surgery.
* Patients who complete the study questionnaires 1 week before surgery and 6 months after surgery.
* Individuals who use at least one of the following social media platforms: Instagram, WhatsApp, Snapchat, X, TikTok, or Telegram.
* Individuals who provide written informed consent to participate in the study.
* Patients scheduled to undergo treatment at the Faculty of Dentistry, Kırıkkale University.

Exclusion Criteria:

* Patients without an indication for bimaxillary orthognathic surgery or those undergoing single-jaw surgery only.
* Individuals with systemic diseases (e.g., diabetes mellitus, hypertension, or thyroid disorders).
* Patients with a diagnosed psychiatric disorder.
* Patients with a history of previous orthognathic surgery.
* Patients scheduled to undergo additional esthetic procedures (e.g., genioplasty, botulinum toxin injection, or dermal filler treatment).
* Individuals who decline to participate or do not provide written informed consent.

Where it's running

  • Kırıkkale University Faculty of Dentistry
    Kirikkale, Kırıkkale, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: Elif Çoban, DDS — Kırıkkale University Faculty of Dentistry
  • Study coordinator: Elif Assistant Professor, DDS
  • Email: elifcoban@kku.edu.tr
  • Phone: +90 318 224 4927

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.