Heavy strength training for survivors of head and neck cancer

Feasibility and Preliminary Efficacy of Heavy Lifting Strength Training Versus Usual Care in Head and Neck Cancer Survivors: A Randomized Controlled Trial

Phase 2 Interventional University of Alberta · NCT06289049

This study is testing if a heavy strength training program can help survivors of head and neck cancer feel stronger and improve their quality of life compared to regular care.

Quick facts

PhasePhase 2
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Alberta Academic / other
Locations1 site (Edmonton, Alberta)
Trial IDNCT06289049 on ClinicalTrials.gov

What this trial studies

This trial investigates the feasibility and effects of a heavy lifting strength training (HLST) program for survivors of head and neck cancer. It aims to compare the outcomes of HLST against usual care in improving muscular strength, physical function, and quality of life. Participants will undergo assessments including strength tests and evaluations of various health-related quality of life metrics. The study will recruit 60 participants who are at least one year post-treatment and meet specific eligibility criteria.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are at least one year post-treatment for any subtype of head and neck cancer and have adequate shoulder range of motion.

Not a fit: Patients who have recently engaged in strength training or are currently participating in another exercise trial may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the physical functioning and quality of life for head and neck cancer survivors.

How similar studies have performed: While light-to-moderate strength training has shown benefits in similar populations, this study's focus on heavy lifting strength training is novel and has not been extensively tested in head and neck cancer survivors.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* males and females, 18 years of age and older
* any head and neck cancer subtype, stage, and treatment type
* at least 1-year posttreatment with adequate shoulder range of motion (must meet minimum cutpoints for active flexion and abduction to be eligible)
* no unmanaged medical conditions, alcohol, or drug abuse
* approved for exercise by oncologist and a certified exercise physiologist or kinesiologist
* ability to understand and communicate in English

Exclusion Criteria:

* has met the Canadian Physical Activity strength training guidelines within the past one-month: at least two days per week of muscle and bone strength training activities using major muscle groups
* currently involved in a different exercise trial or clinical drug trial

Where this trial is running

Edmonton, Alberta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Head and Neck NeoplasmsHead and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck CarcinomaStrength TrainingExerciseQuality of LifeRandomized Controlled Trial
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.