Health Improvement Program for Osteoporosis in China
Health ImprOvement Program of Bone in China
This study is trying to find out how well a tool for predicting fracture risks works for people over 40 with osteoporosis in China, to help improve their treatment and care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 40 Years to 100 Years |
| Sex | All |
| Sponsor | Second Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Trial ID | NCT05906147 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess fracture risk factors related to osteoporosis in the Chinese population using the WHO's FRAX tool. Preliminary findings suggest that the FRAX estimates may underestimate fracture risks in this demographic. The study will establish a treatment threshold and optimal cutting point for risk prediction based on data collected from individuals over 40 years old who have undergone dual-energy X-ray bone mineral density measurements. Regular follow-ups will be conducted to monitor participants' health and fracture risks.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over 40 years old who have undergone bone mineral density testing and are capable of providing informed consent.
Not a fit: Patients under 40 years of age or those with a history of hip replacement, lumbar surgery, or effective anti-osteoporosis treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could lead to more accurate fracture risk assessments and improved prevention strategies for osteoporosis in the Chinese population.
How similar studies have performed: Other studies have shown success in using fracture risk assessment tools, but this specific approach tailored for the Chinese population is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent Exclusion Criteria: * Under 40 years of age， Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.
Where this trial is running
Changsha, Hunan
- Health Management Center, The Second Xiangya Hospital of Central South University — Changsha, Hunan, China (Recruiting)
Study contacts
- Study coordinator: zhifeng sheng, doctorate
- Email: shengzhifeng@csu.edu.cn
- Phone: 008613574806523
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.