Health Improvement Program for Osteoporosis in China
Official title: Health ImprOvement Program of Bone in China
Run by Second Xiangya Hospital of Central South University · NCT05906147 · Data updated 2026-11-12
This study is trying to find out how well a tool for predicting fracture risks works for people over 40 with osteoporosis in China, to help improve their treatment and care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 40 Years to 100 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Second Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Status | Recruiting |
| Started | February 27, 2021 |
| Main results expected | February 27, 2021 |
| Study ends | February 27, 2031 |
| Registry record updated | June 15, 2023 |
| Trial ID | NCT05906147 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals over 40 years old who have undergone bone mineral density testing and are capable of providing informed consent.
✕Probably not a fit
Patients under 40 years of age or those with a history of hip replacement, lumbar surgery, or effective anti-osteoporosis treatment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess fracture risk factors related to osteoporosis in the Chinese population using the WHO's FRAX tool. Preliminary findings suggest that the FRAX estimates may underestimate fracture risks in this demographic. The study will establish a treatment threshold and optimal cutting point for risk prediction based on data collected from individuals over 40 years old who have undergone dual-energy X-ray bone mineral density measurements. Regular follow-ups will be conducted to monitor participants' health and fracture risks.
Why it matters
Potential benefit: If successful, this program could lead to more accurate fracture risk assessments and improved prevention strategies for osteoporosis in the Chinese population.
How similar studies have gone: Other studies have shown success in using fracture risk assessment tools, but this specific approach tailored for the Chinese population is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent Exclusion Criteria: * Under 40 years of age, Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.
Where it's running
-
Health Management Center, The Second Xiangya Hospital of Central South University
Changsha, Hunan, China Recruiting
Study contacts
- Study coordinator: zhifeng sheng, doctorate
- Email: shengzhifeng@csu.edu.cn
- Phone: 008613574806523
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.