Guideline-based lipid lowering approach in Asia-Pacific patients
Official title: Guideline Oriented Approach To Lipid Lowering In Asia-Pacific (GOAL-ASIA)
Run by Monash University · NCT05325034 · Data updated 2026-11-12
This study tests if a special cholesterol management plan helps people in the hospital for a heart attack feel better compared to standard care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Monash University Academic / other |
| Locations | 22 sites (Wollongong, New South Wales and 21 other locations) |
| Status | Recruiting |
| Started | September 15, 2022 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | October 8, 2026 |
| Trial ID | NCT05325034 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are admitted for Type I myocardial infarction.
✕Probably not a fit
Patients with a baseline LDL level below 1.4 mmol/L or those unlikely to survive beyond 12 months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of a guideline-oriented approach to lipid management in patients hospitalized for Type I myocardial infarction. Participants will be randomly assigned to receive either an early intervention or standard care during their hospital stay, followed by a second phase where the control group will receive the intervention after six months. The intervention includes a 'Cholesterol score card' to facilitate communication between patients and their healthcare providers regarding lipid levels and adherence to therapy. The study is designed to reflect real-world clinical practices and enhance the generalizability of the findings.
Why it matters
Potential benefit: If successful, this approach could significantly improve lipid management and reduce cardiovascular risks in patients with acute coronary syndrome.
How similar studies have gone: Other studies have shown promise in implementing guideline-directed therapies for lipid management, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age * Admission for Type I myocardial infarction Exclusion Criteria: * LDL \<1.4mmol/L at baseline * Unable to provide contact details of primary care physician/general practitioner * Unable to provide written informed consent. * Unlikely to survive \>12 months
Where it's running
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Illawarra Shoalhaven Local Health District
Wollongong, New South Wales, Australia Recruiting -
Cairns & Hinterland Hospital & Health Service
Cairns, Queensland, Australia Recruiting -
Monash Health
Clayton, Victoria, Australia Recruiting -
Western Health
Melbourne, Victoria, Australia Recruiting -
Affiliated Zhongshan Hospital of Dalian University
Dalian, Liaoning, China Recruiting -
All India Institute of Medical Sciences
New Delhi, India Recruiting
Show 16 more locations
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National Cerebral and Cardiovascular Center
Osaka, Japan Recruiting -
National Heart Institute
Kuala Lumpur, Malaysia Recruiting -
University of Malaysia Medical Centre
Kuala Lumpur, Malaysia Recruiting -
National Heart Centre
Singapore, Singapore Recruiting -
National Cheng Kung University Hospital
Tainan, Taiwan Recruiting -
Flinders Medical Centre
Bedford Park, South Australia, Australia Not yet recruiting -
Fukuoka University Hospital
Fukuoka, Japan Not yet recruiting -
Kyorin University Hospital
Mitaka, Japan Not yet recruiting -
Osaka Medical and Pharmaceutical University Hospital
Osaka, Japan Not yet recruiting -
University Teknologi MARA, Hospital UiTM, UiTM Medical Centre
Shah Alam, Selangor, Malaysia Not yet recruiting -
National University Hospital Singapore (NUHS)
Singapore, Singapore Not yet recruiting -
PyeongChon Hallym University Sacred Heart Hospital
Pyeongchon, Gyeonggi Province, South Korea Not yet recruiting -
Kangnam Hallym University Sacred Heart Hospital
Seoul, South Korea Not yet recruiting -
Siriraj Hospital
Bangkok, Thailand Not yet recruiting -
Srinagarind Hospital and Queen Sirikit Heart Center of the Northeast
Khon Kaen, Thailand Not yet recruiting -
Songklanagarind Hospital
Songkhla, Thailand Not yet recruiting
Study contacts
- Principal investigator: Stephen Nicholls, MBBS, PhD — Monash University
- Study coordinator: Julie Butters, BHSc, MBA
- Email: julie.butters@monash.edu
- Phone: 61 434679018
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.