Global registry to track outcomes of chronic total occlusion PCI
Official title: Multicenter Registry of Chronic Total Occlusion Interventions
Run by Minneapolis Heart Institute Foundation · NCT02061436 · Data updated 2026-11-12
This registry tests how doctors perform CTO PCI across multiple centers and what outcomes patients have.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Minneapolis Heart Institute Foundation Academic / other |
| Locations | 48 sites (Phoenix, Arizona and 47 other locations) |
| Status | Recruiting |
| Started | January 2012 |
| Main results expected | January 2030 |
| Study ends | January 2030 |
| Registry record updated | August 19, 2026 |
| Trial ID | NCT02061436 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Patients undergoing CTO PCI at participating centers are eligible to participate.
✕Probably not a fit
Patients not undergoing CTO PCI or not treated at participating centers may not benefit from the registry findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational, multicenter registry that collects data on patients undergoing PCI for chronic total occlusions. It aims to document treatment strategies used and immediate and follow-up outcomes to understand how CTO PCI is being practiced. The study will help quantify how frequently CTO PCI is performed at participating sites and describe procedural approaches and results. Data are gathered from several centers to provide real-world insights into CTO intervention practices.
Why it matters
Potential benefit: If successful, the registry could clarify which strategies lead to better outcomes for CTO PCI and guide future practice patterns.
How similar studies have gone: Previous observational registries have shown variability in CTO PCI techniques and outcomes; this study contributes real-world data but its impact depends on consistent data collection across sites.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing CTO PCI at each of the participating centers. Exclusion Criteria: * None
Where it's running
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Little Rock VA Medical Center
Little Rock, Arkansas, United States Recruiting -
San Diego VAMC and University of California
San Diego, California, United States Recruiting -
Medical Center of the Rockies
Loveland, Colorado, United States Recruiting -
Memorial Hospital
Jacksonville, Florida, United States Recruiting -
Emory University Hospital- Emory Heart and Vascular Center
Atlanta, Georgia, United States Recruiting -
Wellstar Health System
Marietta, Georgia, United States Recruiting
Show 42 more locations
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St. Vincent Heart Center
Indianapolis, Indiana, United States Recruiting -
Tulane University Heart and Vascular Institute
New Orleans, Louisiana, United States Recruiting -
Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting -
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States Recruiting -
Henry Ford Medical Center
Detroit, Michigan, United States Recruiting -
Minneapolis Heart Institute
Minneapolis, Minnesota, United States Recruiting -
Minneapolis VA Healthcare System and University of Minnesota
Minneapolis, Minnesota, United States Recruiting -
Maimonides Medical Center
Brooklyn, New York, United States Recruiting -
Trinity Medical WNY
Buffalo, New York, United States Recruiting -
Columbia University
New York, New York, United States Recruiting -
Carolina East Medical Center
New Bern, North Carolina, United States Recruiting -
The Christ Hospital Ohio Heart & Vascular
Cincinnati, Ohio, United States Recruiting -
University Hospitals (UH) Case Western Reserve University
Cleveland, Ohio, United States Recruiting -
Cleveland Clinic
Cleveland, Ohio, United States Recruiting -
Kettering Health Network
Kettering, Ohio, United States Recruiting -
Oklahoma City VA Medical Center
Oklahoma City, Oklahoma, United States Recruiting -
Oklahoma Heart Institute at Hillcrest Medical Center
Tulsa, Oklahoma, United States Recruiting -
Providence Heart & Vascular Institute
Portland, Oregon, United States Recruiting -
University of Pittsburgh Medical Center Presbyterian
Pittsburgh, Pennsylvania, United States Recruiting -
WellSpan Heart & Vascular
York, Pennsylvania, United States Recruiting -
Tristar Centennial Medical Center
Nashville, Tennessee, United States Recruiting -
University of Texas Southwestern Medical Center
Dallas, Texas, United States Recruiting -
VA Dallas Medical Center
Dallas, Texas, United States Recruiting -
Baylor Heart and Vascular Hospital
Dallas, Texas, United States Recruiting -
Baylor Scott & White Research Institute-The Heart Hospital Baylor Plano
Plano, Texas, United States Recruiting -
Baylor Scott and White Research Institute/ The Heart Hospital Baylor Plano
Plano, Texas, United States Recruiting -
The Heart Hospital Baylor Plano
Plano, Texas, United States Recruiting -
St. Boniface General Hospital
Winnipeg, Manitoba, Canada Recruiting -
Aswan Heart Centre
Aswān, Egypt Recruiting -
Korgialeneio-Benakeio Hellenic Red Cross General Hospital of Athens
Athens, Attica, Greece Recruiting -
Henry Hunant Hospital Center
Athens, Greece Recruiting -
St. George Hospital University Medical Center
Beirut, Lebanon Recruiting -
Meshalkin Novosibirsk Research Institute
Novosibirsk, Novosibirsk Oblast, Russia Recruiting -
Banner Samaritan Health Center
Phoenix, Arizona, United States Completed -
Torrance Memorial Medical Center
Torrance, California, United States Active not recruiting -
Piedmont Heart Institute
Atlanta, Georgia, United States Active not recruiting -
Northwestern Bluhm Cardiovascular Institute
Chicago, Illinois, United States Active not recruiting -
Mid America Heart Institute
Kansas City, Missouri, United States Active not recruiting -
Houston Methodist Hospital
Houston, Texas, United States Active not recruiting -
Providence Health Center
Waco, Texas, United States Active not recruiting -
Peacehealth Cardiology
Bellingham, Washington, United States Active not recruiting -
Appleton Cardiology
Appleton, Wisconsin, United States Completed
Study contacts
- Principal investigator: Emmanouil S Brilakis, MD, PhD — Minneapolis Heart Institute Foundation
- Study coordinator: Emmanouil S Brilakis, MD, PhD
- Email: esbrilakis@gmail.com
- Phone: (214) 857-1547
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.