Global registry for patients with type 2 diabetes and related conditions
Official title: Real-world Multinational Registry to Determine Management and Quality of Care of Patients With Type 2 Diabetes, Hypertension, Heart Failure and/or Chronic Kidney Diseases
Run by AstraZeneca · NCT03549754 · Data updated 2026-11-12
This study is collecting information from doctors around the world about patients with type 2 diabetes and related health issues to better understand how these conditions are managed and treated.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 35000 (estimated) |
| Sponsor | AstraZeneca Industry-sponsored |
| Locations | 76 sites (Fortaleza, Ceará and 75 other locations) |
| Status | Recruiting |
| Started | February 17, 2018 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT03549754 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are adults aged 18 and older diagnosed with type 2 diabetes, hypertension, heart failure, and/or chronic kidney disease.
✕Probably not a fit
Patients with life-threatening co-morbidities and a life expectancy of less than one year may not benefit from participation in this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry aims to collect real-world data on patient characteristics, disease management, healthcare utilization, and outcomes for individuals with type 2 diabetes, hypertension, heart failure, and chronic kidney disease. It will utilize a cloud-based electronic case report form (eCRF) for both prospective and retrospective data collection, making it accessible to investigators and a Scientific Committee. The registry is open to physicians worldwide who manage these conditions, facilitating a comprehensive understanding of patient care in clinical practice.
Why it matters
Potential benefit: If successful, this registry could enhance the understanding of disease management and improve healthcare outcomes for patients with these chronic conditions.
How similar studies have gone: Other observational registries have successfully provided valuable insights into chronic disease management, indicating that this approach is both tested and beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Being 18 years or older 2. Having type 2 diabetes, Hypertension, Heart Failure and/or chronic kidney disease 3. Providing written informed consent to participate in the registry Exclusion Criteria: 1. Having a life-threatening co-morbidity with life expectancy below 1 year 2. Participating in an interventional trial requiring informed consent
Where it's running
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Fortaleza, Ceará, Brazil Recruiting -
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Colatina, Espírito Santo (ES), Brazil Recruiting -
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Salvador, Estado de Bahia, Brazil Recruiting -
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Brasília, Federal District, Brazil Recruiting -
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Poços de Caldas, Minas Gerais, Brazil Recruiting -
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Campina Grande do Sul, Paraná, Brazil Recruiting
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Curitiba, Paraná, Brazil Recruiting -
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Teresina, Piauí (PI), Brazil Recruiting -
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Santa Cruz do Sul, Rio Grande Do Sul (RS), Brazil Recruiting -
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Goiânia, State of Goias, Brazil Recruiting -
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Joinville, State of Santa Catarina, Brazil Recruiting -
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Bragança Paulista, São Paulo, Brazil Recruiting -
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São Caetano do Sul, São Paulo, Brazil Recruiting -
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São Paulo, Brazil Recruiting -
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São Paulo, Brazil Recruiting -
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Providencia, Santiago Metropolitan, Chile Recruiting -
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San José, Costa Rica Recruiting -
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Abidjan, Côte d’Ivoire Recruiting -
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Alexandria, Egypt Recruiting -
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Cairo, Egypt Recruiting -
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Giza, Egypt Recruiting -
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Tbilisi, Georgia Recruiting -
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Kumasi, Ghana Recruiting -
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Wan Chai, Hong Kong Recruiting -
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Ahmedabad, India Recruiting -
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Kolkata, India Recruiting -
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Mumbai, India Recruiting -
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Sulaymaniyah, Iraq Recruiting -
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Aktobe, Kazakhstan Recruiting -
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Almaty, Kazakhstan Recruiting -
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Almaty, Kazakhstan Recruiting -
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Almaty, Kazakhstan Recruiting -
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Almaty, Kazakhstan Recruiting -
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Nairobi, Kenya Recruiting -
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Kuala Lumpur, Malaysia Recruiting -
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León, Guanajuato, Mexico Recruiting -
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Iztapalapa, Mexico Recruiting -
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Mexico City, Mexico Recruiting -
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Mexico City, Mexico Recruiting -
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México, Mexico Recruiting -
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Enugu, Nigeria Recruiting -
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Gwagwalada, Nigeria Recruiting -
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Kano, Nigeria Recruiting -
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Cebu City, Philippines Recruiting -
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Florida, South Africa Recruiting -
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Parow, South Africa Recruiting -
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Umhlanga, South Africa Recruiting -
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Umhlanga, South Africa Recruiting -
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Changhua, Taiwan Recruiting -
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Kaohsiung City, Taiwan Recruiting
+26 more sites. See ClinicalTrials.gov for the full list.
Study contacts
- Study coordinator: AstraZeneca Clinical Study Information Center
- Email: information.center@astrazeneca.com
- Phone: 1-877-240-9479
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Adapting and testing PEN-Plus in Zambian primary care
Aiming to see if the PEN-Plus package can be adapted and used in two Zambian hospitals to better manage chronic diseases like heart disease, diabetes, hypertension, and sickle cell in primary care.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.