Global Reference Ranges for Healthy Adults in Singapore

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Global Reference Range Study (GRR) collects MRI data from self-reported healthy adults to generate reference values for fibroinflammation, fat, organ sizes, and other abdominal and thoracic measurements. It aims to determine ethnicity-specific reference ranges when applicable. Enrollment requires adults 18+, willing to consent, and eligible for MRI with no major cardiovascular or organ-related contraindications. The study is observational and led by Perspectum with the National Heart Centre Singapore as a collaborator at a Singapore site.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female at least 18 years of age
* Self-reported healthy
* Willing and able to give informed consent for participation in the study
* Willing and able to undergo an MRI

Exclusion Criteria:

* History of cardiovascular disease as follows:

  * Myocardial infarction
  * Heart failure
  * Cardiomyopathy
  * Stroke
  * Hospital admission/discharge for unstable angina
  * Heart surgery
  * Unstable angina
  * Transient ischemic attack
* Presence of CVD risk factors such as hypertension, hyperlipidaemia, Type 2 diabetes, BMI \> 30 kg/m2, smoker (current/ex-smoker)
* History of non-cardiac diseases related to the lungs, liver, kidneys, pancreas or spleen judged by the study investigator as therefore unsuitable to participate in the study
* The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MRI exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia)
* Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study

Where it's running

• National Heart Centre Singapore
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Masliza Mahmod
• Email: masliza.mahmod@perspectum.com
• Phone: 001865655343

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.