Improving MRI techniques for multiple organs in healthy volunteers
Official title: Research and Development of Novel Quantitative Magnetic Resonance Imaging (MRI) Techniques in a Single Scan for Multiple Organ Application (RADIUS)
Run by Perspectum · NCT05110248 · Data updated 2026-11-12
This study is testing new MRI techniques on healthy volunteers to see if they can improve the quality and consistency of scans for different organs.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Perspectum Industry-sponsored |
| Locations | 1 site (Oxford, Oxfordshire) |
| Status | Recruiting |
| Started | November 15, 2021 |
| Main results expected | March 1, 2031 |
| Study ends | April 30, 2031 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT05110248 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults aged 18 years and older who can provide informed consent.
✕Probably not a fit
Patients with contraindications to MRI or significant health issues that may affect their participation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance MRI data acquisition techniques by optimizing MRI sequences for various organs. It will involve up to 200 healthy participants who will undergo a screening process followed by two MRI scans to assess the repeatability and reproducibility of multiparametric MRI. Participants will be recruited through various channels, including social media and Perspectum's networks, and will provide informed consent before participation.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and efficient MRI techniques that benefit future patients requiring imaging for multiple organ assessments.
How similar studies have gone: While there have been advancements in MRI techniques, this specific approach to optimizing multiparametric MRI in a single scan is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years and older * Participant is willing and able to give informed consent for participation in the study * The participant has a level of English proficiency that allows them to communicate well with the investigator and could comply with study requirements. * The participant is willing and able to undergo MRI scan. Exclusion Criteria: * Any contraindication to magnetic resonance imaging (incl. pregnancy, nonremovable electronic implants including cochlear implants, infusion pumps, and pacemakers, shrapnel injury, severe claustrophobia, allergic reaction to contrast agents) * Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study * The participant may be excluded where body habitus is likely to make MRI or echocardiography/ultrasound uncomfortable or unlikely to yield analysable images, and BMI more than 40-45
Where it's running
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Gemini One, 5520 John Smith Drive
Oxford, Oxfordshire, United Kingdom Recruiting
Study contacts
- Study coordinator: Soubera M Rymell, MSc
- Email: soubera.rymell@perspectum.com
- Phone: 00447313272482
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.