Genetic Risk Profiling in Prostate Cancer: Patient and Provider Perspectives
Official title: Exploring the Patient and Provider Perspectives on the Utility of Genetic Risk Profiling for Prostate Cancer in Routine Clinical Practice
Run by Royal Marsden NHS Foundation Trust · NCT07741929 · Data updated 2026-11-12
This study asks patients and their doctors how genetic risk profiling for prostate cancer might fit into routine care and decision-making.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | Men only |
| Enrollment | 40 (estimated) |
| Sponsor | Royal Marsden NHS Foundation Trust Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | May 1, 2026 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | August 3, 2026 |
| Trial ID | NCT07741929 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults assigned male at birth who have undergone genetic risk profiling for prostate cancer and can provide informed consent, with diverse backgrounds and from those who have or have not benefited from profiling.
✕Probably not a fit
Some participants may not perceive personal benefit if results are inconclusive or not actionable in their care.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This qualitative, observational study interviews patients who have received genetic risk profiling for prostate cancer and the healthcare professionals who delivered the results. It aims to understand how results are perceived and used in clinical practice, including potential benefits, limitations, and practicalities of implementation. The findings will inform future research and help shape how genetic risk information could be integrated into routine care. The study seeks diverse input from people of different ages, ethnicities, and risk levels, and from various clinical settings within the participating sites.
Why it matters
Potential benefit: If successful, insights could support more patient-centered use of genetic risk profiling and help clinicians tailor screening and management decisions.
How similar studies have gone: Prior qualitative work has explored stakeholder views on genetic testing in oncology, suggesting that patient and provider perspectives can inform practical implementation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals assigned male at birth who are aged 18 and over and who have capacity to consent * Patients who have undergone genetic risk profiling for prostate cancer and have received their results * Individuals from diverse backgrounds (age, ethnicity, risk status, etc) * Healthcare providers who have delivered a genetic risk profiling result for prostate cancer Exclusion Criteria: * Individuals who lack capacity to consent * Individuals deemed unsuitable to recruit based on their poor performance status or current medical condition
Where it's running
-
The Royal Marsden Hospital (Sutton and Chelsea)
London, United Kingdom Recruiting
Study contacts
- Principal investigator: Elizabeth Bancroft, RN PhD — The Royal Marsden NHS Foundation Trust / The Institute of Cancer Research
- Study coordinator: Tarryn Shaw, MSc
- Email: tarryn.shaw@rmh.nhs.uk
- Phone: 020 8661 3375
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.