Clinical trial Recruiting at 1 site Observational Ages 18 to 100 Men only

Genetic Risk Profiling in Prostate Cancer: Patient and Provider Perspectives

Official title: Exploring the Patient and Provider Perspectives on the Utility of Genetic Risk Profiling for Prostate Cancer in Routine Clinical Practice

Run by Royal Marsden NHS Foundation Trust · NCT07741929 · Data updated 2026-11-12

This study asks patients and their doctors how genetic risk profiling for prostate cancer might fit into routine care and decision-making.

More Prostate Cancer trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexMen only
Enrollment40 (estimated)
SponsorRoyal Marsden NHS Foundation Trust
Academic / other
Locations1 site (London)
StatusRecruiting
StartedMay 1, 2026
Main results expectedAugust 31, 2027
Study endsAugust 31, 2027
Registry record updatedAugust 3, 2026
Trial IDNCT07741929 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults assigned male at birth who have undergone genetic risk profiling for prostate cancer and can provide informed consent, with diverse backgrounds and from those who have or have not benefited from profiling.

Probably not a fit

Some participants may not perceive personal benefit if results are inconclusive or not actionable in their care.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This qualitative, observational study interviews patients who have received genetic risk profiling for prostate cancer and the healthcare professionals who delivered the results. It aims to understand how results are perceived and used in clinical practice, including potential benefits, limitations, and practicalities of implementation. The findings will inform future research and help shape how genetic risk information could be integrated into routine care. The study seeks diverse input from people of different ages, ethnicities, and risk levels, and from various clinical settings within the participating sites.

Why it matters

Potential benefit: If successful, insights could support more patient-centered use of genetic risk profiling and help clinicians tailor screening and management decisions.

How similar studies have gone: Prior qualitative work has explored stakeholder views on genetic testing in oncology, suggesting that patient and provider perspectives can inform practical implementation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals assigned male at birth who are aged 18 and over and who have capacity to consent
* Patients who have undergone genetic risk profiling for prostate cancer and have received their results
* Individuals from diverse backgrounds (age, ethnicity, risk status, etc)
* Healthcare providers who have delivered a genetic risk profiling result for prostate cancer

Exclusion Criteria:

* Individuals who lack capacity to consent
* Individuals deemed unsuitable to recruit based on their poor performance status or current medical condition

Where it's running

  • The Royal Marsden Hospital (Sutton and Chelsea)
    London, United Kingdom
    Recruiting

Study contacts

  • Principal investigator: Elizabeth Bancroft, RN PhD — The Royal Marsden NHS Foundation Trust / The Institute of Cancer Research
  • Study coordinator: Tarryn Shaw, MSc
  • Email: tarryn.shaw@rmh.nhs.uk
  • Phone: 020 8661 3375

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.