Sponsor or institution

Clinical trials and research at Royal Marsden NHS Foundation Trust

• 30Clinical trials
• 3Countries

Newest trials

All recruiting trials (30)

• Genetic Risk Profiling in Prostate Cancer: Patient and Provider Perspectives

  This study asks patients and their doctors how genetic risk profiling for prostate cancer might fit into routine care and decision-making.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07741929

• Short-course CT online-adaptive radiotherapy for post-operative endometrial cancer

  This trial tests whether delivering post-operative radiotherapy in 5 sessions using CT online-adaptive radiotherapy is safe and feasible for endometrial cancer patients.

  Recruiting Royal Marsden NHS Foundation Trust · Sutton · NCT07675733

• ctDNA-guided precision care for lung, GIST, colorectal, biliary, and ovarian cancers

  This trial tests a blood test that looks for tumor DNA in patients with several cancers to help guide personalized treatment decisions.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07673861

• Personalised neoadjuvant therapy planning for adults with high‑risk soft tissue sarcoma

  This project tests whether analyzing tumor tissue and clinical data can help guide neoadjuvant chemotherapy decisions for adults with high‑risk soft tissue sarcomas.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07432932

• Digital exercise program with live virtual group sessions for men on hormone therapy during radiotherapy

  This program will test whether a digital exercise program with live virtual group sessions helps men with prostate cancer who are starting or receiving hormone therapy with radiotherapy stick to exercise recommendations and improve health and fatigue.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07243834

• Immediate breast reconstruction using 3D imaging and simulation to measure effects of radiotherapy

  This project will test whether 3D surface photos and simulated images help women having a mastectomy with immediate reconstruction feel more confident about their likely appearance, help surgeons plan to reduce later correction surgery, and measure how radiotherapy changes breast shape.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07136753

• Serial multisite image-guided biopsies to track breast cancer evolution

  The team will try taking repeated image-guided biopsies and blood samples from adults with metastatic or advanced breast cancer to see how their tumors change during treatment.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07084571

• Collecting blood and viable tumor samples from people with oncogene-driven or neoadjuvantly treated non-small cell lung cancer.

  This project will try to see if paired blood and viable tumor samples can be reliably collected from adults with oncogene-driven advanced NSCLC starting targeted therapy and from adults with stage II–III NSCLC receiving neoadjuvant immunotherapy.

  Recruiting Royal Marsden NHS Foundation Trust · London, United Kingdom · NCT07008742

• High-dose radiotherapy for renal cell carcinoma treatment

  This study is testing whether a higher dose of radiation therapy can be a better option for people with kidney cancer compared to the standard treatment.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT06995664

• Increasing radiotherapy doses for rectal cancer treatment

  This study tests if giving a higher dose of radiation can help people with advanced rectal cancer avoid surgery by seeing if it leads to better treatment results.

  Recruiting Royal Marsden NHS Foundation Trust · Sutton, Surrey · NCT06854679

• Using video capsules to examine patients with Lynch Syndrome

  This study is testing whether video capsules can be a good alternative to regular colonoscopies for people with Lynch Syndrome to help improve cancer screening.

  Recruiting Royal Marsden NHS Foundation Trust · London, (Select) · NCT06712095

• Understanding breast cancer response during pre-surgery treatment

  This study is trying to see how breast cancer responds to treatment before surgery by looking at tissue and blood samples from patients to find out what factors might affect their recovery and risk of cancer coming back.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT06681064

• Two-session MR‑Linac radiotherapy with targeted dose reduction for intermediate‑risk prostate cancer

  This trial tests whether two MR‑guided radiotherapy sessions with a lower dose to non‑tumor prostate tissue can reduce side effects for men with intermediate‑risk prostate cancer while keeping tumor control.

  Recruiting at 2 sites Royal Marsden NHS Foundation Trust · Toronto and 2 other locations · NCT06638541

• Using PSMA-PET to guide melanoma surgery planning

  We will see if a PSMA PET/CT scan can find melanoma spread more clearly than the standard FDG PET/CT in adults with palpable lymph nodes or limited metastatic melanoma who are scheduled for surgery.

  Recruiting Phase 2 Royal Marsden NHS Foundation Trust · London · NCT06560905

• Mobile health outreach for men's cancer screening

  This study is testing a mobile health service that brings cancer screening directly to men at their workplaces, especially those in high-risk groups, to help them get checked for prostate cancer and other urological issues.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT06357416

• Transoral robotic surgery for early oropharyngeal cancer

  This study is testing how well transoral robotic surgery works for people with early-stage throat cancer and whether it helps them avoid cancer coming back, while also looking at any complications and other factors that might affect their recovery.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT05933889

• Developing tests to identify cancer in patients with vague symptoms

  This study is testing new blood and non-blood tests to see if they can quickly identify cancer in people with unclear but worrying symptoms.

  Recruiting at 10 sites Royal Marsden NHS Foundation Trust · Abergavenny and 9 other locations · NCT05876676

• Investigating the role of ctDNA in advanced thyroid cancer

  This study is trying to see if analyzing blood samples for tumor DNA can help doctors better understand and treat advanced thyroid cancer.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT05837260

• CLIMB: using scans and tissue biomarkers to learn more about primary CNS lymphoma

  This project will try to use brain scans and tumour tissue from adults with newly diagnosed primary CNS lymphoma to find markers that predict treatment response and time without disease progression.

  Recruiting Royal Marsden NHS Foundation Trust · Sutton · NCT05828628

• Investigating outcomes after salvage surgery for recurrent head and neck cancer

  This study tests how well salvage surgery works for people with recurrent head and neck cancer and looks at how genetics and past treatments might affect their recovery and quality of life.

  Recruiting at 8 sites Royal Marsden NHS Foundation Trust · Derby and 8 other locations · NCT05808920

• Collecting cancer samples to create living models for research

  This study is collecting cancer samples from patients to create lab-grown models that help researchers understand why some cancers respond to treatment better than others.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT05734963

• Reducing radiation doses in prostate cancer treatment using advanced technology

  This study is testing whether using advanced technology can safely lower radiation doses in men with intermediate risk prostate cancer while still keeping their PSA levels under control.

  Recruiting Royal Marsden NHS Foundation Trust · Sutton, Surrey · NCT05709496

• Blood biomarker study for early lung cancer diagnosis

  This study is testing if certain blood markers can help tell if lung nodules are harmless or cancerous in patients who have had lung cancer before.

  Recruiting at 9 sites Royal Marsden NHS Foundation Trust · Goodmayes, Essex and 8 other locations · NCT05432739

• Understanding immune-related toxicities in cancer patients receiving therapy

  This study is trying to learn more about the side effects that cancer patients may experience while receiving a new type of treatment called immune checkpoint inhibitors.

  Recruiting Royal Marsden NHS Foundation Trust · Chelsea, London · NCT05331066

• Evaluation of new magnetic resonance imaging techniques

  This study is testing new MRI techniques on patients and healthy volunteers to see if they provide better images and measurements than the standard methods.

  Recruiting Royal Marsden NHS Foundation Trust · Sutton, Surrey · NCT05118555

• Reducing chemotherapy for early-stage breast cancer

  This study is testing if checking blood for tumor DNA can help doctors decide if some early-stage breast cancer patients can safely have less chemotherapy after surgery.

  Recruiting at 13 sites Royal Marsden NHS Foundation Trust · Truro, Cornwall and 12 other locations · NCT05058183

• Detecting and treating early breast cancer relapse using ctDNA analysis

  This study is testing if checking for cancer DNA in the blood can help catch early breast cancer relapses in women with a specific type of breast cancer and see if treating those at risk with a new combination of medications can improve their chances of staying cancer-free.

  Recruiting at 42 sites Phase 2 Royal Marsden NHS Foundation Trust · Angers and 48 other locations · NCT04985266

• Exploring cancer evolution in patients with head and neck tumors after radiation therapy

  This study is trying to understand how head and neck tumors change after radiation therapy to help doctors find better treatments for patients with these cancers.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT04671940

• Tracking mutations in blood to predict relapse in early colorectal cancer

  This study is testing if tracking certain DNA changes in the blood can help predict if people with early colorectal cancer will have a relapse after surgery.

  Recruiting at 66 sites Royal Marsden NHS Foundation Trust · Milton Keynes, Buckinghamshire and 70 other locations · NCT04050345

• Analyzing leftover tumor tissue for better cancer diagnosis

  This study is testing if blending leftover tumor tissue from cancer surgeries can help create better samples for diagnosing cancer more accurately.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT03832062

Quick answers

How many clinical trials run by Royal Marsden NHS Foundation Trust are recruiting right now?

30, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United Kingdom (30 trials), Canada (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →