Fetal Heart Function in Growth-Restricted Pregnancies
Official title: Evaluation of Systolic and Diastolic Cardiac Functions in Fetuses With IUGR
Run by Assiut University · NCT07760194 · Data updated 2026-11-12
This study tests whether fetal echocardiography using a modified Tei index (Mod-MPI) can reveal early heart changes in pregnancies affected by fetal growth restriction (IUGR).
Quick facts
| Study type | Observational |
|---|---|
| Sex | Women only |
| Enrollment | 28 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Status | Recruiting |
| Started | August 2026 |
| Main results expected | September 2026 |
| Study ends | September 2026 |
| Registry record updated | August 13, 2026 |
| Trial ID | NCT07760194 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women greater than 28 weeks gestation with pregnancies affected by intrauterine growth restriction.
✕Probably not a fit
Pregnancies without evidence of growth restriction or where fetal heart function is not altered by chronic hypoxia may not show added benefit from this assessment.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines fetal heart function in pregnancies complicated by intrauterine growth restriction. Researchers use echocardiography and a modified myocardial performance index (Mod-MPI) to assess systolic and diastolic performance, aiming to identify early cardiac changes linked to chronic hypoxia and blood flow redistribution. Eligible participants are pregnant women beyond 28 weeks gestation undergoing routine care at the Women’s Health Hospital in Asyut, Egypt, with no intrauterine fetal death at enrollment. The study builds on prior work suggesting Mod-MPI alterations may reflect evolving cardiac stress in IUGR fetuses.
Why it matters
Potential benefit: If successful, this approach could help clinicians identify fetuses at risk for worsening cardiac function in IUGR pregnancies, enabling closer monitoring and timely interventions.
How similar studies have gone: Previous studies have indicated potential usefulness of Mod-MPI in detecting early fetal cardiac changes in IUGR, supporting the rationale for further observational evaluation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * pregnant women * more than 28 weehs gestation Exclusion Criteria: * intrauterine fetal death
Where it's running
-
Women's Health Hospital
Asyut, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed Fekry
- Email: mohamedbeethoven2040@gmail.com
- Phone: +20882312388
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.