Combined first-trimester screening for pregnancy complications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This national, prospective multicenter pilot will enroll about 2,000 pregnant women in the Czech Republic at 11–13 weeks of gestation. It collects maternal history, ultrasound measurements, biochemical and biophysical parameters and uses FMF‑certified software to calculate individual risks for preeclampsia, fetal growth restriction and common chromosomal aneuploidies. Collected clinical parameters will be linked with the Czech National Health Information System to enable unified recording, analysis and planning for reimbursement mechanisms. The project aims to standardize first‑trimester evaluation across participating centers and improve access to quality prenatal care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A woman over 18 years old in the first trimester of pregnancy (11th-13th gestational week)
* Signed the Consent to Participate in the Project and GDPR.

Exclusion Criteria:

* Unsigned the Consent to Participate in the Project and the Consent to the Processing of Personal Data.

Where it's running

• Regional Health Corpotarion - Most Hospital
  Most, Czechia, Czechia Recruiting
• University Hospital Olomouc
  Olomouc, Czechia, Czechia Recruiting
• Institute for the Care of Mother and Child
  Prague, Czechia, Czechia Recruiting

Study contacts

• Study coordinator: Petra Brlica Heideová, Msc.
• Email: Petra.BrlicaHeideova@uzis.cz
• Phone: +420 770 171 533

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Origins, features, and effects of preeclampsia on mother and baby

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.