Fast- vs slow-absorbing sutures in ultra tension-reducing closure
Official title: A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture Technique
Run by Lanzhou University Second Hospital · NCT07639372 · Data updated 2026-11-12
This study tests whether slow-absorbing sutures lead to better scar outcomes than fast-absorbing sutures in a single patient at a time after a linear surgical incision.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Lanzhou University Second Hospital Academic / other |
| Locations | 1 site (Lanzhou, Gansu) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | September 2026 |
| Study ends | December 2026 |
| Registry record updated | June 10, 2026 |
| Trial ID | NCT07639372 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults undergoing dermatologic surgery with linear closures of 5 cm or longer and willing to follow postoperative visits.
✕Probably not a fit
Patients with infected wounds, non-linear closures, or who do not complete follow-up may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, evaluator-blinded, self-controlled trial in the plastic surgery department at The Second Hospital of Lanzhou University. Each participant receives both suture types on matched wound segments within the same incision: slow-absorbing PDS on Segment A and fast-absorbing Vicryl on Segment B, with standardized closure techniques and postoperative care. Follow-up visits occur at 1 week, 1 month, and 3 months to assess scar formation and healing. The study aims to clarify whether sustained dermal support from slower-absorbing sutures improves hypertrophic scar prevention under ultra tension-reducing closure. Eligible participants have clean incisions of at least 5 cm and are scheduled for dermatologic linear wound closure.
Why it matters
Potential benefit: If successful, patients may experience improved scar appearance and reduced hypertrophic scar risk with slow-absorbing sutures.
How similar studies have gone: Prior evidence suggests slow-absorbing sutures can improve scar outcomes, though results vary by setting and technique.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Incision length ≥ 5 cm; 2. Clean, non-infected surgical wounds; 3. Ability to provide written informed consent voluntarily; 4. Scheduled for dermatologic surgery with intended linear wound closure; 5. Able to complete required postoperative follow-up; 6. No restriction on surgical site. Exclusion Criteria: 1. Incision length ≤ 5 cm; 2. Infected or contaminated wounds; 3. Cognitive impairment precluding provision of independent informed consent; 4. Pregnant women; 5. Any other conditions judged inappropriate for enrollment by investigators.
Where it's running
-
The Second Hospital of Lanzhou University
Lanzhou, Gansu, China Recruiting
Study contacts
- Principal investigator: Zhenzhen Zhang, MM — Lanzhou University Second Hospital
- Study coordinator: Zhenzhen Zhang, MM
- Email: 18153957828@163.com
- Phone: +86 18153957828
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.