Clinical trial Recruiting at 1 site Interventional

Fast- vs slow-absorbing sutures in ultra tension-reducing closure

Official title: A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture Technique

Run by Lanzhou University Second Hospital · NCT07639372 · Data updated 2026-11-12

This study tests whether slow-absorbing sutures lead to better scar outcomes than fast-absorbing sutures in a single patient at a time after a linear surgical incision.

Quick facts

Study typeInterventional
SexAll
Enrollment20 (estimated)
SponsorLanzhou University Second Hospital
Academic / other
Locations1 site (Lanzhou, Gansu)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedSeptember 2026
Study endsDecember 2026
Registry record updatedJune 10, 2026
Trial IDNCT07639372 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults undergoing dermatologic surgery with linear closures of 5 cm or longer and willing to follow postoperative visits.

Probably not a fit

Patients with infected wounds, non-linear closures, or who do not complete follow-up may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, evaluator-blinded, self-controlled trial in the plastic surgery department at The Second Hospital of Lanzhou University. Each participant receives both suture types on matched wound segments within the same incision: slow-absorbing PDS on Segment A and fast-absorbing Vicryl on Segment B, with standardized closure techniques and postoperative care. Follow-up visits occur at 1 week, 1 month, and 3 months to assess scar formation and healing. The study aims to clarify whether sustained dermal support from slower-absorbing sutures improves hypertrophic scar prevention under ultra tension-reducing closure. Eligible participants have clean incisions of at least 5 cm and are scheduled for dermatologic linear wound closure.

Why it matters

Potential benefit: If successful, patients may experience improved scar appearance and reduced hypertrophic scar risk with slow-absorbing sutures.

How similar studies have gone: Prior evidence suggests slow-absorbing sutures can improve scar outcomes, though results vary by setting and technique.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Incision length ≥ 5 cm;
2. Clean, non-infected surgical wounds;
3. Ability to provide written informed consent voluntarily;
4. Scheduled for dermatologic surgery with intended linear wound closure;
5. Able to complete required postoperative follow-up;
6. No restriction on surgical site.

Exclusion Criteria:

1. Incision length ≤ 5 cm;
2. Infected or contaminated wounds;
3. Cognitive impairment precluding provision of independent informed consent;
4. Pregnant women;
5. Any other conditions judged inappropriate for enrollment by investigators.

Where it's running

  • The Second Hospital of Lanzhou University
    Lanzhou, Gansu, China
    Recruiting

Study contacts

  • Principal investigator: Zhenzhen Zhang, MM — Lanzhou University Second Hospital
  • Study coordinator: Zhenzhen Zhang, MM
  • Email: 18153957828@163.com
  • Phone: +86 18153957828

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.