Negative-pressure suction during flexible ureteroscopy to reduce fluid absorption and infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational comparison of patients undergoing retrograde intrarenal surgery (RIRS) with a negative-pressure suction sheath versus a standard sheath without suction. Researchers will collect routine clinical data from adults (18+) treated at the hospital to measure irrigation fluid absorption and postoperative infection outcomes such as fever, SIRS, and urosepsis. No experimental interventions are added—the surgeries occur as part of usual care and data are recorded from medical records. The goal is to determine whether suction technology is associated with lower fluid absorption and fewer infectious complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 years and older with kidney stones who meet the surgical indications for RIRS;
* Patients who have provided informed consent.

Exclusion Criteria:

* Concurrent combination with other surgical procedures, such as percutaneous nephrolithotomy (PCNL);
* Patients with malignancies, urinary tuberculosis, immune system diseases, or hyperthyroidism;
* Congenital renal anomalies, such as polycystic kidney disease or horseshoe kidney;
* Presence of untreated urinary tract infections;
* Inability to tolerate surgery due to severe cardiopulmonary dysfunction, hepatic or renal insufficiency, or coagulation abnormalities.

Where it's running

• Lanzhou University Second Hospital
  Lanzhou, Gansu, China Recruiting

Study contacts

• Study coordinator: Zhiping Wang
• Email: wangzplzu@163.com
• Phone: 13893131697

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Modified Mini-PCNL vs Standard PCNL for Complex Kidney Stones

  This study tests whether a smaller 20 Fr access in modified mini-PCNL can match the stone-clearing success of the standard 24 Fr PCNL in adults with complex kidney stones.

  Recruiting The First Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT07697677

• Aspirating vs non-aspirating ureteral access sheath in RIRS for kidney stones

  This trial tests whether using an aspirating ureteral access sheath during retrograde intrarenal surgery improves stone clearance and reduces complications compared with a non-aspirating sheath in adults with small kidney stones.

  Recruiting Hitit University · Çorum, Çorum · NCT07568990

• Suction to collapse the kidney's collecting system after RIRS (retrograde intrarenal surgery)

  This trial will test whether actively suctioning the kidney's collecting system at the end of RIRS reduces early postoperative pain and infections for adults having kidney stone removal.

  Recruiting Kangdong Sacred Heart Hospital · Gandong-gu, Outside U.S./Canada · NCT07535281

• Compare two suction ureteroscope devices for kidney stones (FANS vs CVAC)

  This study tests whether two new suction-enabled ureteroscopes (FANS and CVAC) lead to better stone clearance for adults with small to medium kidney stones compared to each other.

  Recruiting Ohio State University · Columbus, Ohio · NCT07514351

• Outcomes and costs with the HugeMed 6.3 Fr flexible ureteroscope

  This trial will test whether the HugeMed 6.3 Fr flexible ureteroscope gives similar stone-free results while lowering costs compared with traditional flexible ureteroscopes in adults having RIRS for stones up to 2.5 cm.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT07296835

• MODULITH SLX-F2 shockwave treatment with StorM-Track versus standard targeting for kidney stones

  This will test if using StorM-Track real-time stone tracking with the MODULITH SLX-F2 shockwave machine helps adults with 6–15 mm kidney stones become stone-free more often than standard shockwave treatment.

  Recruiting Storz Medical AG · Stockholm · NCT07272720

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.