Fasciotomy and Predilation for Radial Artery Grafts in CABG

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests whether performing fasciotomy and predilation on radial artery grafts during CABG improves outcomes compared with the standard harvesting method. The approach involves a small tissue release around the graft and pre-procedure dilation with a solution to assess and potentially reduce graft damage. Participants are adults planned for CABG who will receive radial artery grafts. The trial looks at death, heart attack, need for additional procedures, graft failure, and blood flow at 1 year, with safety monitoring throughout. The study is conducted at Ruijin Hospital in Shanghai, led by Ruijin Hospital with no listed collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled for coronary artery bypass grafting (CABG) and planned use of radial artery (RA) grafts

Exclusion Criteria:

* Emergency CABG or redo CABG
* Planned concomitant cardiac or non-cardiac surgery
* Contraindications to coronary computed tomography angiography (CCTA), including pregnancy, uncontrolled severe iodine contrast allergy, or severe renal insufficiency (eGFR \< 30 mL/min/1.73 m²)
* Any condition that, in the investigator's judgment, would preclude safe participation, completion of informed consent, or follow-up
* Inability to provide written informed consent

Where it's running

• Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Yunpeng Zhu — Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China
• Study coordinator: Yunpeng Zhu
• Email: zyp12220@rjh.com.cn
• Phone: +86 02164370045

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.