Exploring therapy options for post-COVID-19 syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of psychotherapy, physical rehabilitation, and a combination of both on fatigue in patients suffering from post-COVID-19 syndrome. Participants will be randomly assigned to one of three intervention groups and will receive therapeutic online sessions for 50 minutes every two weeks over a three-month period. The study aims to evaluate how these interventions impact fatigue levels and exercise capacity, with a follow-up period to assess sustainability of the benefits. The trial will also consider factors such as sex, gender, and BMI in the assignment of participants to ensure balanced groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged over 18 and
* diagnosed post-Covid-19 syndrome: (positive PCR or antibody test) and Fatigue Assessment Scale (FAS) ≥ 22 points

Exclusion Criteria:

* Current participation in another intervention study
* Illnesses or functional disorders that potentially explain the fatigue symptoms otherwise
* Any illness or impairment that the examining physician judges to preclude participation in a physical training intervention
* Suicidality or severe mental illness (e.g. mania, acute phase of schizophrenia) that requires acute treatment.

Where it's running

• Hannover Medical School
  Hannover, Lower Saxony, Germany Recruiting

Study contacts

• Principal investigator: Uwe Tegtbur — Hannover Medical School, Institute for Sports Medicine
• Study coordinator: Sebastian Beyer
• Email: beyer.sebastian@mh-hannover.de
• Phone: +49511532

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How your daily body clock relates to breathing, activity, and nutrition after COVID-19

  This project tests whether morning, intermediate, or evening circadian types relate to respiratory muscle strength, physical activity, sleep, and eating habits in adults with post-COVID-19 syndrome.

  Recruiting Hacettepe University · Ankara, Altindağ · NCT07545499

• Kneipp cold-water hydrotherapy for people with Long COVID

  This randomized trial will test whether regular Kneipp cold-water hydrotherapy can improve quality of life for people with Post‑COVID Syndrome.

  Recruiting Eggensberger OHG · Füssen, Bavaria · NCT07110714

• Functional inspiratory muscle and core stabilization training for people with post-COVID-19 syndrome

  This trial will test whether adding inspiratory muscle training to core stabilization helps adults with post-COVID-19 syndrome improve breathing strength, trunk endurance, exercise capacity, and symptoms like fatigue and breathlessness.

  Recruiting Hacettepe University · Ankara, Çankaya · NCT07051954

• Using Transcranial Pulse Stimulation to treat Post-COVID-19 symptoms

  This study is testing if a new brain stimulation treatment can help people with lingering neurological symptoms after COVID-19, like fatigue and memory issues.

  Recruiting Medical University of Vienna · Vienna, State of Vienna · NCT06178952

• Rehabilitation program to reduce fatigue after COVID-19

  This study is testing a new rehabilitation program called COVIDEx to see if it can help people with Long COVID feel less tired compared to standard care.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06156176

• Yoga vs Health Education for Persistent Post-COVID Fatigue

  This trial will test whether adding a structured yoga program or health education to routine care helps reduce persistent fatigue in adults who had COVID-19.

  Recruiting University Hospital Tuebingen · Stuttgart · NCT05890599

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.