Exploring therapy options for post-COVID-19 syndrome
Randomized Comparison of a Telemedicine-supported Psychosomatic Intervention, a Physical Activity Intervention and the Combination of Both in Patients with Post-covid19 Syndrom.
This study is testing whether psychotherapy, physical rehab, or a mix of both can help reduce fatigue in people dealing with post-COVID-19 syndrome.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 195 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hannover Medical School Academic / other |
| Locations | 1 site (Hannover, Lower Saxony) |
| Trial ID | NCT06042751 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of psychotherapy, physical rehabilitation, and a combination of both on fatigue in patients suffering from post-COVID-19 syndrome. Participants will be randomly assigned to one of three intervention groups and will receive therapeutic online sessions for 50 minutes every two weeks over a three-month period. The study aims to evaluate how these interventions impact fatigue levels and exercise capacity, with a follow-up period to assess sustainability of the benefits. The trial will also consider factors such as sex, gender, and BMI in the assignment of participants to ensure balanced groups.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 diagnosed with post-COVID-19 syndrome and experiencing significant fatigue.
Not a fit: Patients with severe mental illness or other conditions that could explain their fatigue symptoms may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide tailored therapeutic options for improving fatigue in post-COVID-19 patients.
How similar studies have performed: While there is limited research specifically on the combination of these therapies for post-COVID-19 syndrome, similar approaches have shown promise in other fatigue-related conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged over 18 and * diagnosed post-Covid-19 syndrome: (positive PCR or antibody test) and Fatigue Assessment Scale (FAS) ≥ 22 points Exclusion Criteria: * Current participation in another intervention study * Illnesses or functional disorders that potentially explain the fatigue symptoms otherwise * Any illness or impairment that the examining physician judges to preclude participation in a physical training intervention * Suicidality or severe mental illness (e.g. mania, acute phase of schizophrenia) that requires acute treatment.
Where this trial is running
Hannover, Lower Saxony
- Hannover Medical School — Hannover, Lower Saxony, Germany (Recruiting)
Study contacts
- Principal investigator: Uwe Tegtbur — Hannover Medical School, Institute for Sports Medicine
- Study coordinator: Sebastian Beyer
- Email: beyer.sebastian@mh-hannover.de
- Phone: +49511532
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.