Functional inspiratory muscle and core stabilization training for people with post-COVID-19 syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with post-COVID-19 syndrome will be randomized to 8 weeks of core stabilization exercises alone or core stabilization combined with functional inspiratory muscle training, with sessions three times weekly lasting about 50 minutes. Comprehensive pre- and post-intervention assessments include exercise capacity, respiratory and peripheral muscle strength, trunk endurance, balance, and measures of anxiety, depression, and fatigue. Primary outcomes are respiratory muscle strength and trunk muscle endurance, and randomization is stratified by key variables using computer-assisted methods. Participants are aged 18–65, Turkish-speaking, literate, clinically stable, and classified as PCFS functional class 2–3.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with Post-COVID-19 Syndrome.
* Literate and able to understand study procedures.
* Aged between 18 and 65 years.
* Willing to voluntarily participate in the study.
* Classified as functional class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS).
* Clinically stable; comorbid conditions such as hypertension or diabetes must be controlled.
* No orthopedic or neurological conditions that would prevent assessment of peripheral muscle strength, balance, or exercise capacity.

Exclusion Criteria:

* History of recent myocardial infarction or pulmonary embolism.
* Presence of uncontrolled chronic diseases.
* Any orthopedic or neurological disorders that limit mobility.
* Neurological impairments (e.g., cerebrovascular disease) or psychiatric disorders that impair cooperation or compliance with exercise testing.

Where it's running

• Hacettepe University
  Ankara, Çankaya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: EBRU CALIK, Professor — Hacettepe University
• Study coordinator: Ebru Calik, PhD
• Email: ecalik85@gmail.com
• Phone: +905442850087

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.