Exploring the link between periodontal disease and repeated miscarriages
Official title: Status Report on Periodontal Status and Oral Microbiota Women Who Have Suffered Repeated Miscarriages: a Pilot Study
Run by University Hospital, Toulouse · NCT06576622 · Data updated 2026-11-12
This study is trying to see if there’s a connection between gum disease and women who have had multiple miscarriages.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | Women only |
| Enrollment | 30 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Status | Recruiting |
| Started | November 29, 2024 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | May 12, 2026 |
| Trial ID | NCT06576622 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women who have had at least three miscarriages and possess a minimum of six natural teeth.
✕Probably not a fit
Patients currently undergoing antibiotic, prebiotic, or probiotic treatments, or those with a high infection risk, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational pilot study aims to recruit women who have experienced repeated miscarriages, defined as having at least three miscarriages. Participants will undergo a routine oral clinical and radiological examination at the Toulouse University Hospital, where saliva and subgingival plaque samples will be collected for bacterial analysis. The study will also gather information on participants' medical history and risk factors related to periodontal disease. The goal is to investigate the potential relationship between oral health and miscarriage rates.
Why it matters
Potential benefit: If successful, this study could provide insights into how periodontal health impacts miscarriage rates, potentially leading to improved care for women experiencing repeated miscarriages.
How similar studies have gone: While the relationship between oral health and pregnancy outcomes is being explored, this specific approach is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * women whom had repeated miscarriages * at least 6 natural teeth Exclusion Criteria: * under antibiotic prebiotic or probiotics treatment one month prior to the study * with high infection risk (HIV,...)
Where it's running
-
UH Toulouse
Toulouse, France Recruiting
Study contacts
- Study coordinator: alexia VINEL, md
- Email: vinel.a@chu-toulouse.fr
- Phone: +33 5 61 32 25 09
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.