Exploring the link between periodontal disease and repeated miscarriages
Status Report on Periodontal Status and Oral Microbiota Women Who Have Suffered Repeated Miscarriages: a Pilot Study
This study is trying to see if there’s a connection between gum disease and women who have had multiple miscarriages.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | N/A to 18 Years |
| Sex | Female |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Trial ID | NCT06576622 on ClinicalTrials.gov |
What this trial studies
This observational pilot study aims to recruit women who have experienced repeated miscarriages, defined as having at least three miscarriages. Participants will undergo a routine oral clinical and radiological examination at the Toulouse University Hospital, where saliva and subgingival plaque samples will be collected for bacterial analysis. The study will also gather information on participants' medical history and risk factors related to periodontal disease. The goal is to investigate the potential relationship between oral health and miscarriage rates.
Who should consider this trial
Good fit: Ideal candidates for this study are women who have had at least three miscarriages and possess a minimum of six natural teeth.
Not a fit: Patients currently undergoing antibiotic, prebiotic, or probiotic treatments, or those with a high infection risk, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how periodontal health impacts miscarriage rates, potentially leading to improved care for women experiencing repeated miscarriages.
How similar studies have performed: While the relationship between oral health and pregnancy outcomes is being explored, this specific approach is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * women whom had repeated miscarriages * at least 6 natural teeth Exclusion Criteria: * under antibiotic prebiotic or probiotics treatment one month prior to the study * with high infection risk (HIV,...)
Where this trial is running
Toulouse
- UH Toulouse — Toulouse, France (Recruiting)
Study contacts
- Study coordinator: alexia VINEL, md
- Email: vinel.a@chu-toulouse.fr
- Phone: +33 5 61 32 25 09
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.