Clinical trial Recruiting at 1 site Observational Ages Any age to 18 Women only

Exploring the link between periodontal disease and repeated miscarriages

Official title: Status Report on Periodontal Status and Oral Microbiota Women Who Have Suffered Repeated Miscarriages: a Pilot Study

Run by University Hospital, Toulouse · NCT06576622 · Data updated 2026-11-12

This study is trying to see if there’s a connection between gum disease and women who have had multiple miscarriages.

Quick facts

Study typeObservational
AgesAny age to 18 Years
SexWomen only
Enrollment30 (estimated)
SponsorUniversity Hospital, Toulouse
Academic / other
Locations1 site (Toulouse)
StatusRecruiting
StartedNovember 29, 2024
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedMay 12, 2026
Trial IDNCT06576622 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women who have had at least three miscarriages and possess a minimum of six natural teeth.

Probably not a fit

Patients currently undergoing antibiotic, prebiotic, or probiotic treatments, or those with a high infection risk, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot study aims to recruit women who have experienced repeated miscarriages, defined as having at least three miscarriages. Participants will undergo a routine oral clinical and radiological examination at the Toulouse University Hospital, where saliva and subgingival plaque samples will be collected for bacterial analysis. The study will also gather information on participants' medical history and risk factors related to periodontal disease. The goal is to investigate the potential relationship between oral health and miscarriage rates.

Why it matters

Potential benefit: If successful, this study could provide insights into how periodontal health impacts miscarriage rates, potentially leading to improved care for women experiencing repeated miscarriages.

How similar studies have gone: While the relationship between oral health and pregnancy outcomes is being explored, this specific approach is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women whom had repeated miscarriages
* at least 6 natural teeth

Exclusion Criteria:

* under antibiotic prebiotic or probiotics treatment one month prior to the study
* with high infection risk (HIV,...)

Where it's running

  • UH Toulouse
    Toulouse, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.