Evaluating conservative management for retained products of conception and enhanced myometrial vascularity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the therapeutic effects of conservative management on individuals with retained products of conception (RPOC) and enhanced myometrial vascularity (EMV). Participants who have recently experienced a miscarriage or delivery will receive conservative treatments such as mifepristone or expectant management. The study will evaluate the efficacy of these treatments in achieving natural resolution of RPOC over two menstrual cycles. The primary focus is to determine if combining conservative management with EMV can lead to improved outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Recent history of miscarriage or delivery (within the past 8 weeks)
* Strong willingness to undergo conservative management
* Hemodynamically stable
* Signed informed consent form

Exclusion Criteria:

* Heavy vaginal bleeding (requiring immediate surgical intervention)
* Active pelvic or systemic infection (e.g., fever \>38°C, elevated CRP/WBC)
* Severe dysfunction of vital organs (heart, liver, or kidney)
* Known drug allergies or contraindications to proposed medications (e.g., misoprostol intolerance)
* Suspected ectopic pregnancy or gestational trophoblastic disease (confirmed by ultrasound or β-hCG levels)
* Placenta accreta spectrum disorders diagnosed during current pregnancy
* History of uterine artery embolization

Where it's running

• Hysteroscopy Center, Fuxing Hospital, Capital Medical University
  Beijing, China Recruiting

Study contacts

• Study coordinator: Rui Huang
• Email: blueberry0801@foxmail.com
• Phone: +86 18610317613

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.