Exploring the genetics behind congenital heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify genetic causes of congenital heart disease (CHD) using whole genome sequencing (WGS) and traditional genetic techniques. By analyzing genetic material from individuals diagnosed with CHD and their families, the study seeks to uncover the genetic factors contributing to both familial and isolated cases of this common birth defect. The research will involve blood sample collection and data analysis from various cohorts, including families and trios. The goal is to enhance understanding of the genetic underpinnings of CHD, which remains largely unknown despite its prevalence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects must have a diagnosis of Congenital Heart Disease or be related to individuals with Congenital Heart Disease.

Exclusion Criteria:

* Healthy individuals unrelated to those with Congenital Heart Disease

Where it's running

• Nationwide Children's Hospital
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Vidu Garg, MD — Nationwide Children's Hospital
• Study coordinator: Katherine M Spayde, MS, CGC
• Email: katherine.spayde@nationwidechildrens.org
• Phone: 614-355-6388

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.