Exploring how sleep timing and light therapy affect IBD symptoms
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
This study is testing if morning light therapy and changes in sleep timing can help people with inflammatory bowel disease feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 68 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Trial ID | NCT06094608 on ClinicalTrials.gov |
What this trial studies
This pilot study investigates the effects of morning light treatment on individuals with inflammatory bowel disease (IBD) and how changes in sleep timing may influence their symptoms. Participants will use a consumer health light therapy device called Re-Timer to assess its impact on IBD-related quality of life. The study aims to gather data on the relationship between sleep patterns and IBD symptoms, providing insights into potential therapeutic approaches.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with biopsy-proven IBD and active symptoms affecting their quality of life.
Not a fit: Patients with significant chronic diseases, recent light treatment, or severe psychiatric conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the quality of life for patients with inflammatory bowel disease by identifying effective non-pharmacological interventions.
How similar studies have performed: While the specific approach of using light therapy for IBD is novel, similar studies exploring the impact of sleep and light on health outcomes have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Biopsy-proven IBD * Active IBD symptoms * Impaired IBD quality of life * Age \>/=18 years old * Fluency in English * Physically able to travel for study visits Exclusion Criteria: * Ileostomy, colostomy, ileoanal pouch, or ileorectal anastomoses, are planned for imminent surgery and/or have short bowel syndrome * Other significant chronic disease * Retinal pathology, history of eye surgery, taking photosensitizing medications * Recent history of light treatment * Lifetime psychotic or bipolar disorder * Acute suicidal ideation * Substance use disorder in the past 3 months, cannabis use \>1/week * High risk for or diagnosed with obstructive sleep apnea, and/or narcolepsy * Severe hearing problem, intellectual disability or serious cognitive impairment * Pregnant, trying to get pregnant, or breastfeeding * Night work or travel outside the eastern time zone in the past month
Where this trial is running
Ann Arbor, Michigan
- University of Michigan — Ann Arbor, Michigan, United States (Recruiting)
Study contacts
- Principal investigator: Helen Burgess, Ph.D. — University of Michigan
- Study coordinator: Helen Burgess
- Email: bhelen@med.umich.edu
- Phone: 734-615-8303
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.