Exploring gut microbiome in patients with inflammatory bowel disease
Official title: Discovery of Gut Microbial Signatures in Inflammatory Bowel Disease
Run by Kyunghee University Medical Center · NCT03589183 · Data updated 2026-11-12
This study is trying to understand the gut bacteria in Korean patients with inflammatory bowel diseases to see how these bacteria might relate to their health and genetics.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | Kyunghee University Medical Center Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | April 1, 2018 |
| Main results expected | March 31, 2028 |
| Study ends | March 31, 2028 |
| Registry record updated | March 10, 2023 |
| Trial ID | NCT03589183 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals with a confirmed diagnosis of inflammatory bowel disease, specifically ulcerative colitis or Crohn's disease.
✕Probably not a fit
Patients who have used antibiotics or probiotics within the last two weeks may not benefit from this study due to potential confounding effects on the gut microbiome.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on understanding the gut microbiome in Korean patients diagnosed with inflammatory bowel diseases, including ulcerative colitis and Crohn's disease. Researchers will collect various biological samples and comprehensive clinical data to analyze gut microbial signatures and their relationship with clinical and genetic features. The study employs a multi-omics approach, utilizing advanced techniques such as metagenomics, metabolomics, and transcriptomics to build a detailed microbiome library. The goal is to uncover unique microbial patterns that may differ by ethnicity and contribute to the understanding of IBD.
Why it matters
Potential benefit: If successful, this study could lead to personalized treatment strategies for patients with inflammatory bowel disease based on their unique gut microbiome profiles.
How similar studies have gone: While there have been studies on gut microbiome in IBD, this specific approach focusing on a Korean cohort and utilizing a comprehensive multi-omics analysis is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with established diagnosis of inflammatory bowel disease, including ulcerative colitis and Crohn disease Exclusion Criteria: * Person with history of using antibiotics or probiotics within previous 2 weeks.
Where it's running
-
Kyung Hee University Hospital
Seoul, South Korea Recruiting
Study contacts
- Principal investigator: Hyo-Jong Kim, MD PhD — KyungHee University Hospital
- Study coordinator: Chang Kyun Lee, M.D.,Ph.D.
- Email: changkyun.lee@khu.ac.kr
- Phone: 82-2-958-8149
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.