Examining the link between retinal changes and ischemic stroke
Correlation Between the Changes of Retinal Structure and Function and Ischemic Stroke
This study is trying to see if changes in the eyes can help predict the risk of having an ischemic stroke in people who have already had one.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Guangdong Provincial People's Hospital Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05281887 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between retinal structure and function in patients who have experienced ischemic stroke. Using advanced imaging techniques like optical coherence tomography angiography (OCTA) and electroretinogram (ERG), the study aims to identify key retinal parameters that correlate with stroke risk. Additionally, it will analyze the electrical activity of the cerebral cortex through electroencephalogram (EEG) to further understand these correlations. The ultimate goal is to develop a non-invasive risk prediction model for ischemic stroke based on these findings.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have suffered from ischemic stroke.
Not a fit: Patients with other causes of ischemic stroke or existing retinal diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to a new, non-invasive method for predicting stroke risk in patients.
How similar studies have performed: While the approach of using retinal analysis for stroke risk prediction is innovative, similar studies have shown promise in correlating retinal health with cerebrovascular conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with ischemic stroke Exclusion Criteria: * Refractive interstitial turbidity affect the examination results * Any retinal diseases * Other causes of ischemic stroke (cardiogenic embolism, dissection aneurysm, hemagglutination disorder, polycythemia, vasculitis, vascular malformation, etc.) * Fails to complete an ophthalmic examination or the follow-up
Where this trial is running
Guangzhou, Guangdong
- Guangdong Provincial People's Hospital — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Qianli Meng
- Email: mengqly@163.com
- Phone: 13926469923
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.