Clinical trial Recruiting at 1 site Observational Ages 18 and up

Examining the link between retinal changes and ischemic stroke

Official title: Correlation Between the Changes of Retinal Structure and Function and Ischemic Stroke

Run by Guangdong Provincial People's Hospital · NCT05281887 · Data updated 2026-11-12

This study is trying to see if changes in the eyes can help predict the risk of having an ischemic stroke in people who have already had one.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment120 (estimated)
SponsorGuangdong Provincial People's Hospital
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedDecember 1, 2021
Main results expectedDecember 31, 2022
Study endsJanuary 2032
Registry record updatedAugust 9, 2022
Trial IDNCT05281887 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have suffered from ischemic stroke.

Probably not a fit

Patients with other causes of ischemic stroke or existing retinal diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between retinal structure and function in patients who have experienced ischemic stroke. Using advanced imaging techniques like optical coherence tomography angiography (OCTA) and electroretinogram (ERG), the study aims to identify key retinal parameters that correlate with stroke risk. Additionally, it will analyze the electrical activity of the cerebral cortex through electroencephalogram (EEG) to further understand these correlations. The ultimate goal is to develop a non-invasive risk prediction model for ischemic stroke based on these findings.

Why it matters

Potential benefit: If successful, this study could lead to a new, non-invasive method for predicting stroke risk in patients.

How similar studies have gone: While the approach of using retinal analysis for stroke risk prediction is innovative, similar studies have shown promise in correlating retinal health with cerebrovascular conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with ischemic stroke

Exclusion Criteria:

* Refractive interstitial turbidity affect the examination results
* Any retinal diseases
* Other causes of ischemic stroke (cardiogenic embolism, dissection aneurysm, hemagglutination disorder, polycythemia, vasculitis, vascular malformation, etc.)
* Fails to complete an ophthalmic examination or the follow-up

Where it's running

  • Guangdong Provincial People's Hospital
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.