Examining Latent Tuberculosis Infection in Health-care Workers and Students

Cross-sectional Study on Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students. A GENERATOR Infrastructure.

Observational Catholic University of the Sacred Heart · NCT05756582

This study looks at how many health care workers and students have Latent Tuberculosis Infection without symptoms and what factors might put them at risk.

Quick facts

Study typeObservational
Enrollment2040 (estimated)
Ages18 Years to 72 Years
SexAll
SponsorCatholic University of the Sacred Heart Academic / other
Locations1 site (Roma)
Trial IDNCT05756582 on ClinicalTrials.gov

What this trial studies

This observational study investigates the prevalence of Latent Tuberculosis Infection (LTBI) among health care workers and students at Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome. It employs a cross-sectional survey to assess the number of individuals infected with Mycobacterium tuberculosis who show no clinical symptoms of the disease. Additionally, the study aims to identify potential risk factors associated with LTBI in this specific cohort. Participants will complete a questionnaire on dedicated tablets to gather relevant data.

Who should consider this trial

Good fit: Ideal candidates for this study include health care workers and students enrolled in medical programs at the Catholic University of Sacred Heart in Rome.

Not a fit: Patients who are not health care workers or students at the specified institution will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of LTBI prevalence and risk factors, potentially leading to improved screening and prevention strategies.

How similar studies have performed: Other studies have successfully examined LTBI prevalence in similar populations, indicating that this approach is supported by existing research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all health-care workers of Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome,
* all students of all three-year and single-cycle degree courses, master's degree courses, graduate schools of the faculty of Medicine and Surgery of the Catholic University of Sacred Heart in Rome, trained at the Fondazione Policlinico Universitario A. Gemelli IRCCS,
* written informed consent.

Exclusion Criteria:

* denied informed consent.

Where this trial is running

Roma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions TuberculosisTuberculosis, PulmonaryTuberculosis InfectionLatent TuberculosisHealth Care Associated Infectionlatent tuberculosis infectionhealth-care workersstudents
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.