Examining how aerobic exercise affects balance and brain function in adults of different ages
Official title: Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan
Run by University of Minnesota · NCT06127667 · Data updated 2026-11-12
This study tests how a single session of aerobic exercise affects balance and brain function in younger, middle-aged, and older adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 95 Years |
| Sex | All |
| Enrollment | 102 (estimated) |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Status | Recruiting |
| Started | October 15, 2024 |
| Main results expected | July 1, 2028 |
| Study ends | July 1, 2028 |
| Registry record updated | March 27, 2026 |
| Trial ID | NCT06127667 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are neurotypical adults aged 21-30, 40-55, or 65-95 who are cognitively normal and physically able.
✕Probably not a fit
Patients with significant sensory impairments, major orthopedic disabilities, or serious cardiovascular conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the relationship between cerebrovascular health and balance control across different age groups by utilizing a single bout of aerobic exercise. Participants will include younger, middle-aged, and older adults who are neurotypical and cognitively normal. The primary focus is to assess changes in cerebral blood flow during exercise, alongside EEG measures of cortical activity and biomechanical data related to balance. The study aims to enhance our understanding of how aging impacts brain and vascular function.
Why it matters
Potential benefit: If successful, this study could provide insights into how aerobic exercise may improve balance and brain health in aging adults.
How similar studies have gone: While the specific approach of this study may be novel, similar studies have shown that aerobic exercise can positively influence brain health and balance in older adults.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age within the following 3 group age ranges, 21-30yo; middle-aged: 40-55yo; older: 65-95yo adults * the absence of major orthopedic disability * cognitively normal (MoCA score ≥ 26/30 in older adult group) * vision that is 20/40 or better with or without corrective lenses, (5) the ability to consent and communicate with researchers * English speaking * ability to stand for 3 minutes and walk 10 meters with or without an assistive device and without the assistance of another person. Exclusion Criteria: * insulin-dependent diabetes * peripheral neuropathy * myocardial infarction or symptoms of coronary artery disease within 2 years * congestive heart failure or class IV heart failure * any significant sensory impairment affecting balance or cognition; visual, vestibular, or auditory impairments.
Where it's running
-
University of Minnesota
Minneapolis, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Jacqueline Palmer — University of Minnesota
- Study coordinator: Jacqueline Palmer
- Email: brainsinmotion@umn.edu
- Phone: 240-446-1168
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.