Examining how aerobic exercise affects balance and brain function in adults of different ages
Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan
This study tests how a single session of aerobic exercise affects balance and brain function in younger, middle-aged, and older adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 102 (estimated) |
| Ages | 21 Years to 95 Years |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT06127667 on ClinicalTrials.gov |
What this trial studies
This study investigates the relationship between cerebrovascular health and balance control across different age groups by utilizing a single bout of aerobic exercise. Participants will include younger, middle-aged, and older adults who are neurotypical and cognitively normal. The primary focus is to assess changes in cerebral blood flow during exercise, alongside EEG measures of cortical activity and biomechanical data related to balance. The study aims to enhance our understanding of how aging impacts brain and vascular function.
Who should consider this trial
Good fit: Ideal candidates for this study are neurotypical adults aged 21-30, 40-55, or 65-95 who are cognitively normal and physically able.
Not a fit: Patients with significant sensory impairments, major orthopedic disabilities, or serious cardiovascular conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how aerobic exercise may improve balance and brain health in aging adults.
How similar studies have performed: While the specific approach of this study may be novel, similar studies have shown that aerobic exercise can positively influence brain health and balance in older adults.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age within the following 3 group age ranges, 21-30yo; middle-aged: 40-55yo; older: 65-95yo adults * the absence of major orthopedic disability * cognitively normal (MoCA score ≥ 26/30 in older adult group) * vision that is 20/40 or better with or without corrective lenses, (5) the ability to consent and communicate with researchers * English speaking * ability to stand for 3 minutes and walk 10 meters with or without an assistive device and without the assistance of another person. Exclusion Criteria: * insulin-dependent diabetes * peripheral neuropathy * myocardial infarction or symptoms of coronary artery disease within 2 years * congestive heart failure or class IV heart failure * any significant sensory impairment affecting balance or cognition; visual, vestibular, or auditory impairments.
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Jacqueline Palmer — University of Minnesota
- Study coordinator: Jacqueline Palmer
- Email: brainsinmotion@umn.edu
- Phone: 240-446-1168
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.