Examining heart tissue and blood in patients with severe heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects tissue and serum samples from patients with advanced heart disease who are undergoing left ventricular assist device (LVAD) implantation or heart transplantation. The goal is to gather functional, structural, and molecular data to better understand heart failure. Additionally, samples from healthy controls will be used for comparison. The study does not involve any investigational treatments or procedures, focusing solely on data collection and analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \>18 years of age diagnosed with heart failure undergoing either LVAD implantation or heart transplantation
* 13 to 18 years of age, specifically, older children with heart failure whose body mass index is large enough to accommodate and LVAD

Exclusion Criteria:

* Neither patient nor patient representative understands spoken English
* Neither patient nor patient's personal representative is willing to give written consent for participation.

Where it's running

• Intermountain Medical Center
  Murray, Utah, United States Recruiting
• University of Utah Health Sciences Center
  Salt Lake City, Utah, United States Recruiting
• VA Salt Lake City Health Care System
  Salt Lake City, Utah, United States Recruiting

Study contacts

• Principal investigator: Stavros Drakos, M.D., Ph.D. — University of Utah Health Sciences Center & VA Salt Lake City Health Care System
• Study coordinator: John Kirk
• Email: john.kirk@hsc.utah.edu
• Phone: 801-585-2944

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.