Using bioceramic materials to repair bone defects

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of bioceramic implants, specifically β-tricalcium phosphate, in repairing human bone defects. It will explore how the controlled microstructure of these implants can enhance bone regeneration, accelerate recovery, and improve overall bone quality. Participants will be divided into groups receiving either a commercial bone implant or a micro-structured bioceramic implant to assess the outcomes of each approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients who voluntarily take the test and sign the informed consent form;
2. Patients aged 18-65 years old with no history of allergies;
3. Patients able to communicate well with the investigator and follow the requirements of the entire trial.

Exclusion Criteria:

1. Patients who refuse to sign the informed consent form to participate in the trial;
2. Patients who are not in the age range of 18 to 65 years;
3. Patients with diseases unsuitbale for the trial: history of allergies, severe cardiopulmonary disease, coagulation dysfunction, Alzheimer's disease, cerebral atrophy, acute phase or sequelae of cerebrovascular disease, cognitive impairment;
4. Patients in the acute phase of local or systemic bacterial infections;
5. Patients who cannot cooperate with the operation and evaluate the effect;
6. Other conditions that are considered inappropriate by the investigator to participate in the study.

Where it's running

• Nanjing First Hospital
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Qingqiang Yao, phD
• Email: yaoqingqiang@126.com
• Phone: 15366155699

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Arthrosamid versus steroid injections for managing knee osteoarthritis.

  This trial will test whether a single Arthrosamid hydrogel injection works better than a standard steroid plus local anesthetic injection for adults with symptomatic knee osteoarthritis.

  Recruiting Phase 4 Cappagh National Orthopaedic Hospital · Dublin, Dublin · NCT07489521

• All-on-6 upper jaw implants placed with stackable guided surgery and immediate loading

  This study will test whether a fully digital stackable guided surgery workflow with immediate loading works well for adults needing full-arch upper jaw (All-on-6) implants.

  Recruiting Menoufia University · Shibīn al Kawm, Menoufia · NCT07353619

• Guided Equator overdentures for the lower jaw

  This project tests whether fully guided computer-assisted implant placement with Equator attachments gives reliable implant survival and less bone loss for adults with a completely edentulous lower jaw.

  Recruiting Menoufia University · Shibīn al Kawm · NCT07196943

• How three prosthetic methods affect bone levels around dental implants

  This trial will test whether three different prosthetic approaches for posterior dental implants change marginal bone levels around the implant over one year in adults eligible for Lance implants.

  Recruiting Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo · Roma, RM · NCT07156110

• Mandibular overdentures held by four Locator attachments versus a four-implant bar

  This study tests whether mandibular overdentures retained by four Locator attachments or by a four-implant bar better preserve jaw bone in people who have been fully toothless for at least a year.

  Recruiting Menoufia University · Al Mansurah, Menoufia · NCT07093853

• Evaluation of AdvanCore Bone Graft for Bone Healing

  This study is testing if the AdvanCore bone graft can help adults with serious bone defects heal better over a year.

  Recruiting at 2 sites Artur Salgado SA · Guimarães, Braga District and 3 other locations · NCT06736457

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.