Examining endothelial function in patients undergoing non-cardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between endothelial dysfunction and cardiovascular events in patients scheduled for non-cardiac surgery. Researchers will evaluate flow-mediated dilatation of the brachial artery and measure troponin levels before, during, and after surgery. A total of 200 patients aged 45 and older will be enrolled, and their clinical outcomes will be monitored at one, three, and six months post-surgery. The study aims to enhance understanding of how endothelial function impacts surgical outcomes and cardiovascular health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Signed informed consent
* Patients 45 years or older

Exclusion Criteria:

* Refuse to participate in the study
* Myocardial injury or acute myocardial infarction less than two weeks ago
* Patients who expect less than 2 days of hospitalization
* Patients in whom the troponin elevation is attributed to a secondary cause (for example, sepsis, pulmonary thromboembolism, electrical cardioversion, etc.)
* Use of chemotherapy less than 2 weeks ago

Where it's running

• Hospital Clínico de la Universidad de Chile
  Independencia, Santiago Metropolitan, Chile Recruiting

Study contacts

• Study coordinator: Felipe Maldonado, M.D., M.Sc.
• Email: fmaldonado@uchile.cl
• Phone: +56 2 2978 8221

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.