Examining complications from mechanical ventilation in cardiac arrest survivors
Study of Ventilator Associated Event During Intensive Care After Resuscitated Cardiac Arrest.
Centre Hospitalier Sud Francilien · NCT06466980
This study looks at the problems that can happen from using breathing machines in people who survive cardiac arrest to see how these issues affect their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Sud Francilien (other) |
| Locations | 1 site (Corbeil-Essonnes) |
| Trial ID | NCT06466980 on ClinicalTrials.gov |
What this trial studies
This observational study aims to describe the incidence, characteristics, risk factors, and outcomes of complications acquired during mechanical ventilation, known as ventilator-associated events (VAEs), in patients admitted to the intensive care unit after successful resuscitation from cardiac arrest. The study utilizes the new CDC criteria for VAEs to provide a more objective measure of these complications, which are a significant concern for cardiac arrest survivors. By analyzing the data collected from these patients, the study seeks to enhance understanding of the impact of VAEs on morbidity and mortality in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults who have been successfully resuscitated from cardiac arrest and require invasive mechanical ventilation for at least four days.
Not a fit: Patients who have opposed the use of their data or those who require life-sustaining therapies within 24 hours of admission may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients recovering from cardiac arrest, potentially reducing the incidence of complications associated with mechanical ventilation.
How similar studies have performed: Previous studies have shown a significant association between ventilator-associated events and increased morbidity and mortality, indicating that this approach has been validated in similar contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult male or female * Non-pregnant female * Successfully resuscitated from cardiac arrest during primary care * Invasive mechanical ventilation initiated during resuscitation and continued for at least 4 days * No decision to limit life-sustaining therapies within 24 hours following admission to intensive care * No requirement of arteriovenous circulatory support during intensive care management Exclusion Criteria \- patients who opposed to the use of their data
Where this trial is running
Corbeil-Essonnes
- Centre Hospitalier Sud Francilien — Corbeil-Essonnes, France (RECRUITING)
Study contacts
- Study coordinator: Fabrice COOK, MD
- Email: fabrice.cook@chsf.fr
- Phone: 01 61 69 52 28
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiac Arrest With Successful Resuscitation, Mechanical Ventilation, Ventilator associated event, cardiac arrest, ventilator-acquired pneumonia, ventilator associated pneumonia