Examining bone mineral density in adults with cystic fibrosis

Erişkin Kistik Fibrozisli Bireylerde Kemik Mineral Yoğunluğunun Postür, Solunum Fonksiyonları ve Fonksiyonel Egzersiz Kapasitesi Üzerine Etkisi

This study looks at how cystic fibrosis affects bone health and physical abilities in adults aged 18-45.

Quick facts

• Study type: Observational
• Enrollment: 60 (estimated)
• Ages: 18 Years to 45 Years
• Sex: All
• Sponsor: Hacettepe University (Academic / other)
• Locations: 1 site (Ankara)
• Trial ID: NCT06088485 on ClinicalTrials.gov

What this trial studies

This observational study involves 60 voluntary participants aged 18-45 diagnosed with cystic fibrosis. It aims to assess various functional capacities, including respiratory functions, muscle strength, and postural alignment through a series of tests such as the Shuttle Walking Test and the Modified Medical Research Council Dyspnea Scale. Additionally, demographic information and perceptions of cosmetic deformity will be recorded to understand the impact of cystic fibrosis on bone mineral density and overall physical health.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-45 who have been diagnosed with cystic fibrosis.

Not a fit: Patients who have had recent fractures, spine surgery, or other significant orthopedic or neurological conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the relationship between bone mineral density and cystic fibrosis, potentially leading to improved management strategies for affected patients.

How similar studies have performed: While there have been studies on cystic fibrosis and bone health, this specific approach focusing on bone mineral density in this age group is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Patients aged between 18-45 who were diagnosed with Cystic Fibrosis

Exclusion Criteria:

In the last year, patients;

* who had a fracture in any part of the patient's body
* who had undergone spine surgery
* who had an orthopedic, neurological or metastatic history in addition to Cystic Fibrosis

Where this trial is running

Ankara

• Hacettepe University, Health Sciences Faculty — Ankara, Turkey (Recruiting)

Study contacts

• Principal investigator: Aynur Demirel — Hacettepe University
• Study coordinator: Aynur Demirel, PhD

Conditions Cystic Fibrosis; Postural Defect; Pulmonary Disease; Physical Inactivity