Evaluating treatment recommendations for children with nephroblastoma
Official title: Therapeutic Recommendations for the Treatment of Children With Nephroblastoma in Africa.
Run by French Africa Pediatric Oncology Group · NCT04423484 · Data updated 2026-11-12
This study looks at how well hospitals follow treatment guidelines for children with nephroblastoma who haven't had treatment yet, to see if sticking to these guidelines leads to better outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Months to 18 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | French Africa Pediatric Oncology Group Academic / other |
| Locations | 7 sites (Ouagadougou and 6 other locations) |
| Status | Recruiting |
| Started | July 1, 2020 |
| Main results expected | December 31, 2028 |
| Study ends | December 30, 2030 |
| Registry record updated | March 2, 2026 |
| Trial ID | NCT04423484 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children with unilateral nephroblastoma who have not been previously treated and are in good general health.
✕Probably not a fit
Patients with bilateral nephroblastoma, those who have been previously treated, or those with advanced disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess how well medical units adhere to treatment recommendations for nephroblastoma based on findings from two previous studies by the GFAOP. It will focus on treatment compliance and outcomes for children diagnosed with unilateral nephroblastoma who have not received prior treatment. The study will also evaluate improvements in treatment compliance and reporting, which will help tailor future treatment programs to local conditions and needs.
Why it matters
Potential benefit: If successful, this study could enhance treatment compliance and outcomes for children with nephroblastoma.
How similar studies have gone: While this study builds on previous research, its specific approach to evaluating treatment compliance is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Unilateral Nephroblastoma Tumor Not previously treated The general health of the child will permit treatment. . Exclusion Criteria: Bilateral Nephroblastoma tumor Previously treated Disease too advanced Doubt concerning the diagnosis Treatment Refusal
Where it's running
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Centre Hospitalier Universitaire Pédiatrique Charles De Gaulle
Ouagadougou, Burkina Faso Recruiting -
CHU de Treichville à ABIDJAN
Abidjan, Abidjan Autonomous District, Côte d’Ivoire Recruiting -
CUK (Cliniques Universitaires de Kinshasa)
Kinshasa, Democratic Republic of the Congo Recruiting -
Cliniques Universitaires de Lubumbashi (CUL)
Lubumbashi, Democratic Republic of the Congo Recruiting -
HJRA, Hôpital universitaire Joseph Ravoahangy Andrianavalona
Antananarivo, Madagascar Recruiting -
CHU Gabriel Touré (HGT)
Bamako, Mali Recruiting
Show 1 more location
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Hôpital Aristide Le Dantec, Avenue Pasteur, BP 3001
Dakar, Dakar, Senegal Recruiting
Study contacts
- Principal investigator: Fatou Binetou Ms DIAGNE AKONDE, Dr — French Africa Pediatric Oncology Group
- Study coordinator: BRENDA Ms MALLON, MSC
- Email: brenda.mallon@gustaveroussy.fr
- Phone: 0033142115411
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.