Evaluating treatment options for stroke patients presenting after 24 hours

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a registry-linked cohort of patients with acute ischemic stroke caused by large vessel occlusions who present to participating centers more than 24 hours after their last known well time. The study will assess the outcomes of patients treated with endovascular therapy or the best available medical management. By focusing on patients with confirmed large vessel occlusions, the study seeks to fill the knowledge gap regarding the efficacy of endovascular therapy beyond the standard treatment window. Comprehensive patient data will be collected to analyze treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient admitted from Jan. 1st 2018 to Jan. 1st 2028;
* Presenting beyond 24 hours from last known well;
* Ischemic stroke confirmed by head CT or MRI;
* Large vessel occlusion confirmed by head CTA or MRA: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA), and posterior cerebral artery (PCA P1/P2);
* Patients receiving either endovascular therapy or best medical treatment.

Exclusion Criteria:

• Presence of any forms of cerebral hemorrhage on CT/MR at admission.

Where it's running

• Tianjin Huanhu Hospital
  Tianjin, Tianjin Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.