Evaluating the prevalence of pneumonia-causing bacteria using a urine test
Official title: Prospective Study to Evaluate Streptococcus Pneumoniae Serotypes Prevalence in Community Acquired Pneumonia in Hong Kong Using a Urinary Kit
Run by Chinese University of Hong Kong · NCT04647630 · Data updated 2026-11-12
This study is testing a urine test to see how common pneumonia-causing bacteria are in hospitalized patients with community-acquired pneumonia.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1800 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Shatin) |
| Status | Recruiting |
| Started | January 1, 2021 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | February 12, 2025 |
| Trial ID | NCT04647630 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are hospitalized patients showing signs and symptoms of community-acquired pneumonia.
✕Probably not a fit
Patients with pneumonia caused by pathogens other than Streptococcus pneumoniae or those with nosocomial pneumonia will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the prevalence and serotypes of Streptococcus pneumoniae in hospitalized patients diagnosed with community-acquired pneumonia (CAP). Patients admitted with symptoms suggestive of pneumonia will be screened, and those who consent will provide a urine sample for analysis. The urine will be tested for pneumococcal pneumoniae using a urinary antigen assay, with serotyping performed simultaneously. The clinical management of patients will continue as usual, with study personnel only collecting urine samples and not interfering with treatment.
Why it matters
Potential benefit: If successful, this study could improve the understanding of pneumonia-causing bacteria, leading to better-targeted treatments for patients.
How similar studies have gone: Similar studies have shown success in identifying bacterial serotypes using urinary antigen assays, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted with signs and symptoms suggestive of pneumonia Exclusion Criteria: * 1\. Nosocomial pneumonia which is acquired \>= 48 hours after hospital admission. 2. Pneumonia which are already known to be caused by pathogens other than pneumococcus pneumoniae.
Where it's running
-
Department of Medicine and Therapeutics, Prince of Wales Hospital, CUHK
Shatin, Hong Kong Recruiting
Study contacts
- Study coordinator: K W To
- Email: tokw617@yahoo.com.hk
- Phone: 55699297
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.