Evaluating the prevalence of pneumonia-causing bacteria using a urine test
Prospective Study to Evaluate Streptococcus Pneumoniae Serotypes Prevalence in Community Acquired Pneumonia in Hong Kong Using a Urinary Kit
This study is testing a urine test to see how common pneumonia-causing bacteria are in hospitalized patients with community-acquired pneumonia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1800 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Shatin) |
| Trial ID | NCT04647630 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the prevalence and serotypes of Streptococcus pneumoniae in hospitalized patients diagnosed with community-acquired pneumonia (CAP). Patients admitted with symptoms suggestive of pneumonia will be screened, and those who consent will provide a urine sample for analysis. The urine will be tested for pneumococcal pneumoniae using a urinary antigen assay, with serotyping performed simultaneously. The clinical management of patients will continue as usual, with study personnel only collecting urine samples and not interfering with treatment.
Who should consider this trial
Good fit: Ideal candidates are hospitalized patients showing signs and symptoms of community-acquired pneumonia.
Not a fit: Patients with pneumonia caused by pathogens other than Streptococcus pneumoniae or those with nosocomial pneumonia will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the understanding of pneumonia-causing bacteria, leading to better-targeted treatments for patients.
How similar studies have performed: Similar studies have shown success in identifying bacterial serotypes using urinary antigen assays, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted with signs and symptoms suggestive of pneumonia Exclusion Criteria: * 1\. Nosocomial pneumonia which is acquired \>= 48 hours after hospital admission. 2. Pneumonia which are already known to be caused by pathogens other than pneumococcus pneumoniae.
Where this trial is running
Shatin
- Department of Medicine and Therapeutics, Prince of Wales Hospital, CUHK — Shatin, Hong Kong (Recruiting)
Study contacts
- Study coordinator: K W To
- Email: tokw617@yahoo.com.hk
- Phone: 55699297
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.