Evaluating the EchoTip AcuCore device for biopsies

EchoTip AcuCore Post-Market Clinical Study

Cook Group Incorporated · NCT06358001

This study is testing how well the EchoTip AcuCore device works for taking biopsies of different tumors during endoscopic ultrasound procedures to see if it’s effective and safe for patients.

Quick facts

Study typeObservational
Enrollment183 (estimated)
Ages18 Years and up
SexAll
SponsorCook Group Incorporated (industry)
Locations8 sites (Orange, California and 7 other locations)
Trial IDNCT06358001 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather data on the EchoTip AcuCore device's effectiveness in performing endoscopic ultrasound-guided fine-needle biopsies (EUS-FNB) for various types of tumors. It will assess both the favorable outcomes and any potential adverse effects associated with the device. Patients referred for EUS fine needle biopsy procedures will be included, and the EchoTip AcuCore will be the primary device used during these procedures.

Who should consider this trial

Good fit: Ideal candidates are adults referred for an endoscopic ultrasound fine needle biopsy procedure using the EchoTip AcuCore device.

Not a fit: Patients under 18 years old or those with inaccessible lesions will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy and safety of tissue diagnosis for patients with specific types of tumors.

How similar studies have performed: While this study is observational, similar approaches using advanced biopsy techniques have shown promise in improving diagnostic accuracy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient has been referred for an endoscopic ultrasound (EUS) fine needle biopsy procedure
* The EchoTip AcuCore device is the first EUS biopsy needle used in the procedure.

Exclusion Criteria:

* Patient's age is less than 18 years
* Patient is unable or unwilling to sign and date the informed consent. If IRB approves a waiver of consent, this exclusion criterion is not applicable.
* Patient is simultaneously participating in another pre-market investigational drug or pre-market investigational device study involving an EUS fine needle biopsy procedure and for which the patient has not completed the follow-up phase for the primary endpoint at least 30 days prior to enrollment in this study.
* Inaccessible or unsuitable lesion (lesion not visualized or a large vessel, duct or primary mass interposition)

Where this trial is running

Orange, California and 7 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma, Malignant Lymphoma, Metastasis, Chronic Pancreatitis, Autoimmune Pancreatitis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.