Evaluating respiratory functions and exercise capacity in children with neuromuscular diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess respiratory functions, thoracoabdominal movements, and exercise capacity in children diagnosed with Duchenne Muscular Dystrophy (DMD) and Spinal Muscular Atrophy (SMA) compared to healthy controls. Conducted at Lokman Hekim University, the study will include 42 children divided into three groups, each undergoing various tests including spirometry, structured light plethysmography, and functional assessments like the six-minute walk test. The goal is to gather comprehensive data on respiratory and muscular parameters over a 20-month period.

Why it matters

Who can join: the full rules

1. Duchenne Muscular Dystrophy (DMD)

   -Inclusion Criteria: Clinically diagnosed with Duchenne Muscular Dystrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study.

   -Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure.
2. Spinal Muscular Atrophy (SMA)

   -Inclusion Criteria: Clinically diagnosed with Spinal Muscular Atrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study.

   -Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure.
3. Healthy Controls

   * Inclusion Criteria:

No diagnosis of neuromuscular diseases. Age above 5 years. Able to breathe independently. Willing to participate in the study.

-Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure.

Where it's running

• Lokman Hekim University
  Ankara, Çankaya, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Bilge Taşkın Gürel, PhD(c)
• Email: taskinbilge@gmail.com
• Phone: +905348172800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.