Evaluating patients with chronic liver diseases linked to fat accumulation in the liver

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with chronic liver diseases associated with hepatic steatosis, which can lead to serious complications like cirrhosis and liver failure. The study aims to perform in-depth phenotyping at a tissue level to better understand the underlying mechanisms of these diseases and identify potential biomarkers for diagnosis and treatment. It includes adult patients suspected of having various liver conditions, such as non-alcoholic steatohepatitis and autoimmune hepatitis. The research will help clarify the relationship between hepatic steatosis and other chronic liver diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients/healthy control participants (age 18 or above) who can give their informed consent
* Suspected liver disease:
* non-alcoholic steatohepatitis
* alcoholic steatohepatitis
* autoimmune hepatitis
* primary biliary cholangitis
* primary sclerosing cholangitis
* inflammatory bowel disease
* polycystic ovary syndrome
* hereditary haemochromatosis
* chronic pancreatitis
* cystic fibrosis
* alpha-1 antitrypsin deficiency

Exclusion Criteria:

Patients with:

* malignant diseases
* viral hepatitis
* human immunodeficiency virus
* contraindications to liver biopsy

Where it's running

• Hvidovre University Hospital
  Hvidovre, Denmark Recruiting

Study contacts

• Principal investigator: Lise L Gluud, Professor — Hvidovre University Hospital
• Study coordinator: Anne-Sofie H Jensen, MD
• Email: anne-sofie.houlberg.jensen@regionh.dk
• Phone: +4538621966

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.