Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating outcomes of total ankle replacement surgery

Official title: Evaluation of Epidemiology and Radiological and Clinical Outcomes in Total Ankle Prosthesis

Run by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT03650010 · Data updated 2026-11-12

This study looks at how well total ankle replacement surgeries work and what results patients get from different types of ankle implants.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1066 (estimated)
SponsorI.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Academic / other
Locations1 site (Milan, Milano)
StatusRecruiting
StartedMay 11, 2016
Main results expectedMarch 31, 2026
Study endsMarch 31, 2027
Registry record updatedAugust 28, 2018
Trial IDNCT03650010 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who have undergone or will undergo total ankle replacement surgery during the study period.

Probably not a fit

Patients under 18 years of age at the time of surgery will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the clinical and radiological outcomes of total ankle replacement surgeries performed between January 2011 and March 2026. It includes both retrospective and prospective evaluations, focusing on the effectiveness of different types of ankle prosthetics. The study will collect clinical data and radiological parameters through routine evaluations and questionnaires to provide a comprehensive overview of patient outcomes. The findings are expected to fill a gap in the existing literature regarding ankle joint surgeries.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effectiveness of total ankle replacement, improving patient outcomes and guiding future surgical practices.

How similar studies have gone: While few studies have reported on ankle replacement outcomes, this study aims to provide a comprehensive reference, suggesting a novel approach to evaluating these surgeries.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Males and females
* age ≥ 18 years at the time of surgery
* patients who underwent ankle replacement surgery from January 2011 to March 2026

Exclusion Criteria:

\- age \< 18 years at the time of surgery

Where it's running

  • Irccs Istituto Ortopedico Galeazzi
    Milan, Milano, Italy
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.