Evaluating Ketamine Treatment Plans for Chronic Conditions

Understanding the Safety of Home Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation · NCT06038409

This study is testing different ways to use Ketamine for people with chronic pain, depression, and anxiety to see how well it works and if combining it with therapies like talk therapy or music helps improve their conditions.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorRIVER Foundation (other)
Locations1 site (Helena, Montana)
Trial IDNCT06038409 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the efficacy of various off-label approaches to prescribing Ketamine for patients with chronic conditions such as chronic pain, depressive disorder, and anxiety disorders. It will explore the impact of different administration methods (IV, IM, SubQ, Sublingual) and the influence of adjunct therapies like psychotherapy and music therapy on treatment outcomes. Additionally, the study will examine the relationship between Ketamine treatment and suicidal ideation, focusing on how chronic issues may improve with this treatment.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with identifiable chronic conditions who are currently receiving Ketamine treatment.

Not a fit: Patients who are healthy and do not have any chronic conditions will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into optimizing Ketamine treatment plans for patients with chronic conditions, potentially improving their quality of life.

How similar studies have performed: While there have been few studies comparing the impact of different Ketamine administration methods, this study's focus on adjunct therapies and their effects on outcomes is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Must have an identifiable chronic condition.

Exclusion Criteria:

Healthy population

Where this trial is running

Helena, Montana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Chronic Pain, Depressive Disorder, Anxiety Disorders, Chronic Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.