Evaluating hyperbaric oxygen therapy for traumatic brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the safety and long-term effects of hyperbaric oxygen therapy in adults over 18 with traumatic brain injury (TBI). Participants will be monitored for their functional independence and ability to engage in social activities over a two-year period, regardless of whether they have previously received hyperbaric oxygen therapy. The study will involve online or telephone surveys to gather data on cognitive functioning, physical disability, mental status, employment, and social activities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18\~90 years old
2. Patients with traumatic brain injury admitted to the rehabilitation department who met the following inclusion criteria:

1\) Clear history of exogenous trauma-causing disease (such as car accidents, heavy objects, falls, violent assaults, explosive injuries, etc.) 2) GCS score of 3 to 15 points (excluding all kinds of poisoning, sedation, shock factors) 3. Clear presence of at least one of the following imaging signs on cranial CT or MRI: Traumatic intracranial hemorrhage, subdural hematoma, epidural hematoma, cerebral contusion, ventricular hemorrhage, subarachnoid hemorrhage, or brainstem injury; 4. good compliance, signed informed consent, and those who were judged by the investigator to be eligible for enrollment.

Exclusion Criteria:

1. Sequelae of previous spinal cord injury or combination of spinal cord injury in this injury;
2. Severe coagulation disorders;
3. Pregnancy status;
4. Any other factors that the investigator considers to be a potential risk to the subject or that interfere with the subject.

Where it's running

• The Second Affiliated Hospital Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Principal investigator: Zhihua Zhang — Departments of Physical Medithe Second Affiliated Hospital of Zhejiang University School of Medicine
• Study coordinator: Zhihua Zhang
• Email: 2511097@zju.edu.cn
• Phone: +8613757159433

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.