Depth Electrode Monitoring after Traumatic Brain Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a small feasibility study in adults with TBI who need an external ventricular drain. A multi-contact depth electrode will be placed adjacent to the EVD catheter during standard care, with ongoing cortical stimulation and recording to detect patterns related to cortical reverberation and seizures. Recordings are reviewed daily by a neurosurgeon or epileptologist to identify electrographic seizure activity and other signals of interest. The goal is to determine whether this monitoring approach can be implemented safely and provide meaningful information about brain activity after injury.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 18 years or older
2. Consenting party must be able to provide written consent in English
3. Patient recommended to undergo EVD placement for the monitoring and possible treatment of ICP after TBI

Exclusion Criteria:

1. Contaminated scalp lacerations
2. Known systemic infection
3. Non-English speaking
4. Fixed, uncorrectable coagulopathy
5. Pregnant, minors, or wards of the state

Where it's running

• Hennepin Healthcare Research Institute
  Minneapolis, Minnesota, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.