Evaluating changes in facial structure during maxillary expansion with a specialized appliance

Hard and Soft Tissue Changes During Maxillary Expansion Using Skeletally Anchored Appliances: a Prospective, Randomized Clinical Study.

Not applicable Interventional Medical University of Vienna · NCT06246656

This study is testing how a special orthodontic appliance can change the shape of the face in young people aged 12 to 26 during treatment for teeth alignment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment38 (estimated)
Ages12 Years to 26 Years
SexAll
SponsorMedical University of Vienna Academic / other
Locations1 site (Vienna, State of Vienna)
Trial IDNCT06246656 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effects of maxillary expansion on both hard and soft tissues in the midfacial region using a computer-aided design and manufacturing (CAD/CAM) appliance. Participants, aged 12 to 26, will undergo orthodontic treatment that includes the placement of temporary anchorage devices and a fixed multibracket appliance. The study will utilize advanced imaging techniques such as intraoral scans, face scans, and cone-beam computed tomography (CBCT) to assess changes in the bony structures and soft tissues during the treatment process. The goal is to provide a comprehensive understanding of how this innovative approach impacts orthodontic outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents and young adults aged 12 to 26 with a maxillary transverse deficit and lateral crossbite.

Not a fit: Patients who have undergone previous orthodontic treatment, have craniofacial anomalies, severe facial asymmetries, are pregnant, or have periodontal lesions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved orthodontic treatment strategies that enhance facial aesthetics and functional outcomes for patients.

How similar studies have performed: While the use of CAD/CAM technology in orthodontics is gaining traction, this specific approach to evaluating soft and hard tissue changes during maxillary expansion is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Maxillary transverse deficit,
* Lateral crossbite

Exclusion Criteria:

* Previous orthodontic treatment,
* Craniofacial anomalies,
* Severe facial asymmetries,
* Pregnancy,
* Periodontal lesions

Where this trial is running

Vienna, State of Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Palatal Expansion TechniqueCAD/CAMOrthodonticsMaxillary ExpansionSoft Tissue Change
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.