Evaluating changes in facial structure during maxillary expansion with a specialized appliance
Official title: Hard and Soft Tissue Changes During Maxillary Expansion Using Skeletally Anchored Appliances: a Prospective, Randomized Clinical Study.
Run by Medical University of Vienna · NCT06246656 · Data updated 2026-11-12
This study is testing how a special orthodontic appliance can change the shape of the face in young people aged 12 to 26 during treatment for teeth alignment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 12 Years to 26 Years |
| Sex | All |
| Enrollment | 38 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna, State of Vienna) |
| Status | Recruiting |
| Started | January 2, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | September 1, 2026 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT06246656 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adolescents and young adults aged 12 to 26 with a maxillary transverse deficit and lateral crossbite.
✕Probably not a fit
Patients who have undergone previous orthodontic treatment, have craniofacial anomalies, severe facial asymmetries, are pregnant, or have periodontal lesions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effects of maxillary expansion on both hard and soft tissues in the midfacial region using a computer-aided design and manufacturing (CAD/CAM) appliance. Participants, aged 12 to 26, will undergo orthodontic treatment that includes the placement of temporary anchorage devices and a fixed multibracket appliance. The study will utilize advanced imaging techniques such as intraoral scans, face scans, and cone-beam computed tomography (CBCT) to assess changes in the bony structures and soft tissues during the treatment process. The goal is to provide a comprehensive understanding of how this innovative approach impacts orthodontic outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved orthodontic treatment strategies that enhance facial aesthetics and functional outcomes for patients.
How similar studies have gone: While the use of CAD/CAM technology in orthodontics is gaining traction, this specific approach to evaluating soft and hard tissue changes during maxillary expansion is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Maxillary transverse deficit, * Lateral crossbite Exclusion Criteria: * Previous orthodontic treatment, * Craniofacial anomalies, * Severe facial asymmetries, * Pregnancy, * Periodontal lesions
Where it's running
-
Medical University of Vienna, Department of Orthodontics
Vienna, State of Vienna, Austria Recruiting
Study contacts
- Principal investigator: Alexander Schwärzler, DMD — Department of Orthodontics, University Clinic of Dentistry, Medical University of Vienna
- Study coordinator: Sophia Panwinkler, DMD
- Email: sophia.panwinkler@meduniwien.ac.at
- Phone: +431400704301
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.