Effect of early intervention on displaced canine teeth in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of early orthodontic intervention for children with palatally displaced canines. It involves a multicenter, parallel 3-group randomized design across orthodontic departments in Sweden, Germany, and the UK. The study will compare outcomes between children who undergo extraction of the primary canine or space opening for the adult tooth versus those who receive no treatment. The primary outcome is the proportion of participants who avoid surgery after 18 months, while secondary outcomes include cost-effectiveness and the impact on surrounding teeth.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* One or both upper permanent canine teeth are not palpable or there is a pronounced difference in the eruption between the left and right side. Dental radiographs will be taken to confirm that the permanent tooth is displaced. Canines in sector 5 are going to be excluded from this trial.

Exclusion Criteria:

* Buccal displacement of the canine(s), missing permanent lateral incisors; severe upper arch dental crowding (\>2mm in each affected quadrant) or associated pathology.

Where it's running

• Gothenbrug University
  Gothenburg, Sweden Recruiting
• Private practice
  Traben-Trarbach, Germany Not yet recruiting
• University of Sheffield
  Sheffield, United Kingdom Not yet recruiting

Study contacts

• Principal investigator: Farhan Bazargani, DDS, PhD — Gothenburg University, Gothenburg, Sweden
• Study coordinator: Farhan Bazargani, DDS, PhD
• Email: farhan.bazargani@gu.se
• Phone: +46707546107

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.